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瑞典初级卫生保健机构中即时检测肌钙蛋白T的成本后果

Cost consequences of point-of-care troponin T testing in a Swedish primary health care setting.

作者信息

Nilsson Staffan, Andersson Agneta, Janzon Magnus, Karlsson Jan-Erik, Levin Lars-Åke

机构信息

Primary Health Care and Department of Medicine and Health Sciences, Linköping University , Norrköping , Sweden.

出版信息

Scand J Prim Health Care. 2014 Dec;32(4):241-7. doi: 10.3109/02813432.2014.984901. Epub 2014 Dec 1.

Abstract

OBJECTIVE

To evaluate the safety and cost-effectiveness of point-of-care troponin T testing (POCT-TnT) for the management of patients with chest pain in primary care.

DESIGN

Prospective observational study with follow-up.

SETTING

Three primary health care (PHC) centres using POCT-TnT and four PHC centres not using POCT-TnT in south-east Sweden.

PATIENTS

All patients ≥ 35 years of age, contacting one of the PHC centres for chest pain, dyspnoea on exertion, unexplained weakness and/or fatigue, with no other probable cause than cardiac, were included. Symptoms must have commenced or worsened during the previous seven days.

MAIN OUTCOME MEASURES

Emergency referral rates, diagnoses of acute myocardial infarction (AMI) or unstable angina (UA), and costs were collected for 30 days after the patient sought care at the PHC centre.

RESULTS

A total of 196 patients with chest pain were included: 128 in PHC centres with POCT-TnT and 68 in PHC centres without POCT-TnT. Fewer patients from the PHC centres with POCT-TnT (n = 32, 25%) were emergently referred to hospital than from centres without POCT-TnT (n = 29, 43%; p = 0.011). Eight patients (6.2%) from PHC centres with POCT-TnT were diagnosed with AMI or UA compared with six patients (8.8%) from centres without POCT-TnT (p = 0.565). Two patients with AMI or UA were classified as missed cases from PHC centres with POCT-TnT and there were no missed cases from PHC centres without POCT-TnT. SKr290 000 was saved per missed case of AMI or UA.

CONCLUSION

The use of POCT-TnT in primary care may be cost saving but at the expense of missed cases.

摘要

目的

评估即时检测肌钙蛋白T(POCT-TnT)在基层医疗中用于胸痛患者管理的安全性和成本效益。

设计

前瞻性观察性随访研究。

地点

瑞典东南部三个使用POCT-TnT的初级卫生保健(PHC)中心和四个未使用POCT-TnT的PHC中心。

患者

所有年龄≥35岁、因胸痛、劳力性呼吸困难、不明原因的虚弱和/或疲劳而前往其中一个PHC中心就诊,且除心脏原因外无其他可能病因的患者均被纳入。症状必须在过去7天内开始或加重。

主要观察指标

收集患者在PHC中心就诊后30天的紧急转诊率、急性心肌梗死(AMI)或不稳定型心绞痛(UA)的诊断情况以及费用。

结果

共纳入196例胸痛患者:128例来自使用POCT-TnT的PHC中心,68例来自未使用POCT-TnT的PHC中心。与未使用POCT-TnT的中心(n = 29,43%)相比,使用POCT-TnT的PHC中心紧急转诊至医院的患者较少(n = 32,25%;p = 0.011)。使用POCT-TnT的PHC中心有8例患者(6.2%)被诊断为AMI或UA,而未使用POCT-TnT的中心有6例患者(8.8%)被诊断为此类疾病(p = 0.565)。使用POCT-TnT的PHC中心有2例AMI或UA患者被归类为漏诊病例,未使用POCT-TnT的PHC中心无漏诊病例。每漏诊1例AMI或UA可节省290 000瑞典克朗。

结论

在基层医疗中使用POCT-TnT可能节省成本,但代价是出现漏诊病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa0d/4278399/ab7662fbed6c/pri-32-241_g001.jpg

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