Chin Helen B, Johnson Candice Y, Kim Konny H, Knight Jessica H, Mertens Ann C, Mink Pamela J, Simeone Regina M, Woodard Jill J, Howards Penelope P
Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, CNR 3rd Floor, Atlanta, GA, 30322, USA.
Aflac Cancer Center, Department of Pediatrics, Emory University School of Medicine, 2015 Uppergate Road, Atlanta, GA, 30322, USA.
BMC Womens Health. 2014 Nov 30;14:149. doi: 10.1186/s12905-014-0149-y.
Loss of fertility has been reported as an important concern of reproductive age women diagnosed with cancer. The Furthering Understanding of Cancer, Health, and Survivorship In Adult (FUCHSIA) Women's Study examines how cancer treatment affects the fertility of cancer survivors who were diagnosed during their reproductive years. In this paper we discuss the process of developing and pilot testing the FUCHSIA computer assisted telephone interview (CATI).
The CATI was developed in several phases and pilot tested twice to evaluate several aspects of the instrument including question sequencing, understandability of the questions, and women's comfort with certain questions. Participants were recruited from cancer and infertility support groups and study team contacts.
Fifty-two women were recruited and participated in the first pilot. The participants had a mean age of 31.5 years, 17.3% had cancer, and 38.5% experienced a period of infertility. Twenty-four women participated in the second pilot with similar representation.
The collection of detailed information on reproductive outcomes with the CATI may improve the understanding of how cancer treatment during the reproductive years affects female fertility. The pilot studies provided important information to improve the CATI before the full study. Our comprehensive recruitment strategy allowed us to interview a diverse group of women to ensure that questions and answer choices were easily interpreted, check complicated skip patterns and the flow of questions, and evaluate the length of the interview. This experience can be used to help inform others in what steps can be useful for developing telephone interviews for research studies.
据报道，生育能力丧失是被诊断患有癌症的育龄妇女的一个重要担忧。“成人癌症、健康与幸存者深入理解”（FUCHSIA）女性研究考察了癌症治疗如何影响在生育年龄被诊断出癌症的幸存者的生育能力。在本文中，我们讨论了FUCHSIA计算机辅助电话访谈（CATI）的开发和预试验过程。
CATI分几个阶段开发，并进行了两次预试验，以评估该工具的几个方面，包括问题顺序、问题的可理解性以及女性对某些问题的接受程度。参与者从癌症和不孕不育支持小组以及研究团队联系人中招募。
招募了52名女性并参与了第一次预试验。参与者的平均年龄为31.5岁，17.3%患有癌症，38.5%经历过一段时间的不孕不育。24名女性参与了第二次预试验，其代表性相似。
通过CATI收集关于生殖结局的详细信息，可能会增进对生育年龄期间的癌症治疗如何影响女性生育能力的理解。预试验为在全面研究之前改进CATI提供了重要信息。我们全面的招募策略使我们能够采访不同群体的女性，以确保问题和答案选项易于理解，检查复杂的跳答模式和问题流程，并评估访谈时长。这一经验可用于帮助告知他人，哪些步骤对开展研究性电话访谈有用。
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