Department of Pediatric Surgery and Intensive Care, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Radiol Oncol. 2014 Nov 5;48(4):397-402. doi: 10.2478/raon-2013-0080. eCollection 2014 Dec.
Mediastinal fetal teratoma can be detected as a mass in the chest during a routine prenatal ultra-sound screening. Because of the pressure on mediastinal structures it can be the cause of non-immune hydrops fetalis and polyhydramnion. The development of hydrops fetalis leads to fetal death or premature delivery in most reported cases. Early surgical removal is important, but, the result of treatment depends on the stage of development of mediastinal organs and complications in the postoperative period.
A 31-year-old gravida carrying twins, with spontaneous membrane rupture at 32 weeks gestation underwent urgent caesarean section after antenatal ultrasound revealed severe polyhydramnion and hydrops fetalis in geminus A. The child was intubated immediately after birth due to severe respiratory distress. Ultrasound and X-ray revealed a tumour mass in the right hemithorax. Tumour resection was performed at the age of 7 days. Histology examination revealed an encapsulated immature teratoma. The postoperative course was complicated with respiratory insufficiency which turned into chronic at the age of eight months.
This is the fifth reported child with fetal mediastinal teratoma and severe hydrops fetalis that survived the neonatal period. Additional diagnostic search revealed abnormal course of both pulmonary arteries, which was probably one of the main causes of respiratory insufficiency.
纵隔胎儿畸胎瘤在常规产前超声筛查中可被检测为胸部肿块。由于纵隔结构受压,它可能是胎儿非免疫性水肿和羊水过多的原因。在大多数报道的病例中,胎儿水肿的发展导致胎儿死亡或早产。早期手术切除很重要,但治疗结果取决于纵隔器官的发育阶段和术后并发症。
一名 31 岁的经产妇怀双胞胎,孕 32 周时胎膜自然破裂,产前超声显示胎儿 A 严重羊水过多和水肿,随后行紧急剖宫产。由于严重的呼吸窘迫,孩子出生后立即插管。超声和 X 光显示右侧胸腔有一个肿瘤肿块。在 7 天大时进行了肿瘤切除术。组织学检查显示为包裹性未成熟畸胎瘤。术后出现呼吸功能不全,8 个月时转为慢性。
这是第五例报道的胎儿纵隔畸胎瘤和严重胎儿水肿的患儿,新生儿期存活。进一步的诊断性检查显示两条肺动脉异常,这可能是呼吸功能不全的主要原因之一。