不同年龄大鼠心脏和骨骼肌中的抗氧化酶活性。
Antioxidant enzyme activities in heart and skeletal muscle of rats of different ages.
作者信息
Vertechy M, Cooper M B, Ghirardi O, Ramacci M T
机构信息
Biological Research Laboratories, Sigma-Tau S.p.A., Rome, Italy.
出版信息
Exp Gerontol. 1989;24(3):211-8. doi: 10.1016/0531-5565(89)90012-0.
The activity of antioxidant enzymes was measured in cardiac and skeletal muscle in rats aged either 4, 15, or 27 months. Generally, regardless of age, heart contains a greater content of these enzymes than skeletal muscle. Whereas skeletal muscle showed age-dependent increases in glutathione peroxidase, glutathione reductase, and catalase activities, heart tissue showed increases in only the glutathione peroxidase activity. Neither tissue showed any significant age-dependent change in cytosolic or mitochondrial superoxide dismutase content or in cytochrome oxidase.
在4个月、15个月或27个月大的大鼠的心肌和骨骼肌中测量了抗氧化酶的活性。一般来说，无论年龄大小，心脏中这些酶的含量都比骨骼肌中的含量高。骨骼肌中谷胱甘肽过氧化物酶、谷胱甘肽还原酶和过氧化氢酶的活性呈现出随年龄增长而增加的趋势，而心脏组织中仅谷胱甘肽过氧化物酶的活性有所增加。两种组织的胞质或线粒体超氧化物歧化酶含量以及细胞色素氧化酶均未显示出任何随年龄增长而发生的显著变化。
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