Plant Production Technology Section, Faculty of Agricultural Technology, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.
Department of Entomology, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand.
Acta Trop. 2015 Feb;142:127-30. doi: 10.1016/j.actatropica.2014.11.010. Epub 2014 Nov 28.
Repellency activity of Thai essential oils derived from ylang ylang (Cananga odorata (Lamk.) Hook.f. & Thomson: Annonaceae) and lemongrass (Cymbopogon citratus (DC.) Stapf: Poaceae) were tested against two mosquito vectors, Aedes aegypti (L.) and Culex quinquefasciatus (Say). There were compared with two chemical repellents (DEET 20% w/w; Sketolene Shield(®) and IR3535, ethyl butylacetylaminopropionate 12.5% w/w; Johnson's Baby Clear Lotion Anti-Mosquito(®)). Each herbal repellent was applied in three diluents; coconut oil, soybean oil and olive oil at 0.33 μl/cm(2) on the forearm of volunteers. All herbal repellent exhibited higher repellent activity than IR3535 12.5% w/w, but lower repellent activity than DEET 20% w/w. The C. odorata oil in coconut oil exhibited excellent activity with 98.9% protection from bites of A. aegypti for 88.7±10.4 min. In addition, C. citratus in olive oil showed excellent activity with 98.8% protection from bites of C. quinquefasciatus for 170.0±9.0 min. While, DEET 20% w/w gave protection for 155.0±7.1-182.0±12.2 min and 98.5% protection from bites of two mosquito species. However, all herbal repellent provided lower repellency activity (97.4-98.9% protection for 10.5-88.7 min) against A. aegypti than C. quinquefasciatus (98.3-99.2% protection for 60-170 min). Our data exhibited that C. odorata oil and C. citratus oil are suitable to be used as green repellents for mosquito control, which are safe for humans, domestic animals and environmental friendly.
泰国依兰（Cananga odorata (Lamk.) Hook.f. & Thomson：Annonaceae）和柠檬草（Cymbopogon citratus (DC.) Stapf：Poaceae）的精油的驱避活性被测试了对两种蚊子传播媒介，埃及伊蚊（Aedes aegypti (L.)）和致倦库蚊（Culex quinquefasciatus (Say.)）。它们与两种化学驱避剂（20% DEET w/w；Sketolene Shield(®) 和 IR3535，乙基丁基乙酰氨基丙酸盐 12.5% w/w；Johnson's Baby Clear Lotion Anti-Mosquito(®)）进行了比较。每种草药驱避剂都以三种稀释剂（椰子油、大豆油和橄榄油）涂在志愿者的前臂上，浓度为 0.33 μl/cm(2)。所有草药驱避剂的驱避活性均高于 12.5% w/w 的 IR3535，但低于 20% w/w 的 DEET。椰子油中的依兰油表现出优异的活性，对埃及伊蚊的保护率为 98.9%，有效保护时间为 88.7±10.4 分钟。此外，橄榄油中的柠檬草表现出优异的活性，对致倦库蚊的保护率为 98.8%，有效保护时间为 170.0±9.0 分钟。而 20% w/w 的 DEET 对两种蚊子的保护时间为 155.0±7.1-182.0±12.2 分钟，保护率为 98.5%。然而，所有草药驱避剂对埃及伊蚊的驱避活性（10.5-88.7 分钟内 97.4-98.9%的保护率）均低于致倦库蚊（60-170 分钟内 98.3-99.2%的保护率）。我们的数据表明，依兰油和柠檬草油适合作为绿色驱蚊剂用于蚊虫控制，对人类、家畜和环境均安全。
