Lazarides Alexander, Erdmann Detlev, Powers David, Eward William
Medical Student, Duke University School of Medicine, Durham, NC.
Associate Professor, Department of Surgery, Division of Plastic and Reconstructive Surgery, Duke University Medical Center, Durham, NC.
J Oral Maxillofac Surg. 2014 Nov;72(11):2375.e1-10. doi: 10.1016/j.joms.2014.07.018. Epub 2014 Jul 25.
Osteosarcoma accounts for most primary bone cancers in children and young adults. High-grade lesions are typically managed with a combination of chemotherapy and wide-margin surgical excision. Although this malignancy typically affects the metaphyseal region of long bones, it also can be seen in the axial skeleton. Of axial locations, tumors in the head and neck can be particularly troubling to treat. Segmental bone loss after resection of malignant mandibular tumors continues to present important challenges to the reconstructive surgeon. Recent advancements in 3-dimensional modeling have facilitated custom templates for patient-specific reconstructions. This report describes the case of a young woman with osteosarcoma of the mandible undergoing customized template composite facial reconstruction using a vascularized osteoseptocutaneous fibula flap.
骨肉瘤是儿童和青年中最常见的原发性骨癌。高级别病变通常采用化疗和广泛边缘手术切除相结合的方法进行治疗。虽然这种恶性肿瘤通常影响长骨的干骺端区域，但也可见于中轴骨骼。在中轴骨骼部位中，头颈部的肿瘤治疗起来可能特别棘手。恶性下颌肿瘤切除后的节段性骨缺损仍然给重建外科医生带来重大挑战。三维建模的最新进展促进了针对患者的定制重建模板的发展。本报告描述了一名患有下颌骨肉瘤的年轻女性，使用带血管的骨-鼻中隔皮瓣进行定制模板复合面部重建的病例。
