Eissenberg Joel C
Mo Med. 2014 Sep-Oct;111(5):428-33.
The sequence of the human genome represents our genetic blueprint. While it is now possible to draw direct connections between specific DNA sequences and specific physical features and to predict disease risk, the effects of certain genes can be masked by a process called "epigenetics." Here, I summarize our current understanding of epigenetics and it affects gene expression, with impacts on health and aging.
人类基因组序列代表了我们的遗传蓝图。虽然现在已经能够在特定的DNA序列与特定的身体特征之间建立直接联系，并预测疾病风险，但某些基因的作用可能会被一个称为“表观遗传学”的过程所掩盖。在此，我总结了我们目前对表观遗传学及其如何影响基因表达的理解，以及它对健康和衰老的影响。
