Division of Sport Science, Universität Konstanz, Konstanz, Germany.
NeuroRehabilitation. 2013;32(3):655-63. doi: 10.3233/NRE-130888.
The aim of this randomized controlled trial was to test the hypothesis that a three-week whole body vibration (WBV) training in addition to a standard rehabilitation program improves walking ability in patients with Multiple Sclerosis (MS).
Sixty patients with definite MS were randomly allocated to the intervention or control group. Training sessions were performed three times per week for three weeks. Patients adopted a moderate squat position on a vibration platform. The training sessions comprised series of 3 × 60-sec exercise sets with increasing amplitude between sessions from 1 to 2 mm. During the exercise series, the vibration platform was turned on for the intervention group and switched off for the control group. A mixed factor ANOVA was used to compare sit to stand test, timed up and go test, 10-meter walk test, and 6-min walk test data between patient groups and between baseline and follow-up.
All outcome measures improved from baseline to follow-up (P < 0.001). The 6-minute walk test showed significantly greater improvements from baseline to follow-up for the intervention than for the control group (P < 0.001).
Determinants of walking ability in patients with MS that are specific to walking endurance tasks are most affected by vibration training designed to improve strength endurance.
本随机对照试验旨在验证假设，即三周全身振动（WBV）训练结合标准康复方案可改善多发性硬化症（MS）患者的步行能力。
60 名确诊 MS 患者被随机分配至干预组或对照组。每周训练 3 次，共 3 周。患者在振动平台上采用适度深蹲姿势。训练包括 3 组，每组 60 秒，每组之间的振幅逐渐增加，从 1 毫米增加到 2 毫米。在运动系列中，干预组的振动平台开启，对照组关闭。采用混合因素方差分析比较患者组之间以及基线和随访之间的坐站测试、计时起立行走测试、10 米步行测试和 6 分钟步行测试数据。
所有结局指标均从基线到随访有所改善（P<0.001）。与对照组相比，干预组从基线到随访的 6 分钟步行测试改善更为显著（P<0.001）。
针对改善力量耐力而设计的振动训练对与步行耐力任务相关的 MS 患者步行能力的决定因素影响最大。
