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口腔微生物群与口腔癌

The oral microbiome and oral cancer.

作者信息

Wang Laura, Ganly Ian

机构信息

Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

出版信息

Clin Lab Med. 2014 Dec;34(4):711-9. doi: 10.1016/j.cll.2014.08.004. Epub 2014 Sep 15.

DOI:10.1016/j.cll.2014.08.004
PMID:25439271
Abstract

The role that bacteria play in the etiology and predisposition to cancer is of increasing interest, particularly since the development of high-throughput genetic-based assays. With this technology, it has become possible to comprehensively examine entire microbiomes as a functional entity. This article focuses on the understanding of bacteria and its association with oral squamous cell carcinoma.

摘要

细菌在癌症的病因和易感性中所起的作用越来越受到关注，特别是自从基于高通量基因检测技术的发展以来。借助这项技术，将整个微生物群落作为一个功能实体进行全面检测已成为可能。本文着重于对细菌及其与口腔鳞状细胞癌的关联的理解。

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