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[接受骨密度检测的女性中与骨质减少和骨质疏松相关的因素]

[Factors associated with osteopenia and osteoporosis in women undergoing bone mineral density test].

作者信息

Veiga Silva Ana Carolina, da Rosa Maria Inês, Fernandes Bruna, Lumertz Suéli, Diniz Rafaela Maria, dos Reis Damiani Maria Eduarda Fernandes

机构信息

Universidade do Extremo Sul Catarinense, Criciúma, SC, Brasil.

Universidade do Extremo Sul Catarinense, Criciúma, SC, Brasil.

出版信息

Rev Bras Reumatol. 2015 May-Jun;55(3):223-8. doi: 10.1016/j.rbr.2014.08.012. Epub 2014 Oct 24.

DOI:10.1016/j.rbr.2014.08.012
PMID:25440700
Abstract

The aim of this study was to determine the prevalence of osteopenia and osteoporosis in a female population, that had bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) in a specialized clinic in the south of Brazil. We conducted a cross-sectional study including 1,871 women that performed scans between January and December 2012. We conducted a logistic regression analysis with all independent variables and outcomes (osteopenia, osteoporosis and fracture risk). According to DXA results, 36.5% of women had normal BMD, 49.8% were diagnosed with osteopenia and 13.7% with osteoporosis. Menopause and age over 50 years old were risk factors for osteopenia and osteoporosis while prior hysterectomy and BMI greater than 25 were protective factors. For the outcome of fracture at any site the risk factors were age over 50 years old, osteopenia and osteoporosis (OR = 2.09, 95% CI:1,28-3, 40) and (OR = 2.49, 95% CI:1,65-3, 74), respectively.

摘要

本研究的目的是确定在巴西南部一家专科诊所通过双能X线吸收法(DXA)测量骨密度(BMD)的女性人群中骨质减少和骨质疏松症的患病率。我们开展了一项横断面研究,纳入了2012年1月至12月期间进行扫描的1871名女性。我们对所有自变量和结果(骨质减少、骨质疏松症和骨折风险)进行了逻辑回归分析。根据DXA结果,36.5%的女性骨密度正常,49.8%被诊断为骨质减少,13.7%被诊断为骨质疏松症。绝经和50岁以上是骨质减少和骨质疏松症的危险因素,而既往子宫切除术和体重指数大于25是保护因素。对于任何部位骨折的结果,危险因素分别是50岁以上、骨质减少和骨质疏松症(比值比=2.09,95%置信区间:1.28 - 3.40)和(比值比=2.49,95%置信区间:1.65 - 3.74)。

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