[隐球菌病：面部溃疡的一种潜在病因]
[Cryptococcosis: a potential aetiology of facial ulceration].
作者信息
Béogo R, Andonaba J-B, Bamba S, Konségré V, Diallo B, Traoré A
机构信息
Service de stomatologie et de chirurgie maxillo-faciale, CHU Sanou Souro, Bobo-Dioulasso, Burkina Faso.
Service de dermatologie et de vénérologie, CHU Sanou Souro, Bobo-Dioulasso, Burkina Faso.
出版信息
J Mycol Med. 2014 Dec;24(4):e185-8. doi: 10.1016/j.mycmed.2014.03.007.
UNLABELLED
Cutaneous cryptococcosis is an uncommon aetiology of chronic facial ulceration but which may be associated to a potentially lethal focus of cryptococcosis.
OBSERVATION
A 35-year-old AIDS patient under antiretroviral therapy, presented with a chronic facial ulceration. Histopathological examination of a biopsy of the facial ulceration showed an inflammatory granuloma and masses of yeasts. Mycological culture of the cerebrospinal fluid revealed Cryptococcus neoformans. The diagnosis of AIDS-related cutaneous cryptococcosis of the face and cryptococcal meningitis was concluded.
DISCUSSION
Cryptococcosis should be thought as a potential aetiology of a chronic facial ulceration in an AIDS patient. Screening of other foci of the cryptococcosis such as that of the central nervous system is mandatory. Mycological examinations are of great interest for the diagnosis in rare resources setting.
未标注
皮肤隐球菌病是慢性面部溃疡的一种罕见病因，但可能与潜在致命的隐球菌病病灶相关。
观察
一名接受抗逆转录病毒治疗的35岁艾滋病患者出现慢性面部溃疡。面部溃疡活检的组织病理学检查显示有炎性肉芽肿和酵母团块。脑脊液真菌培养发现新型隐球菌。得出艾滋病相关面部皮肤隐球菌病和隐球菌性脑膜炎的诊断。
讨论
隐球菌病应被视为艾滋病患者慢性面部溃疡的潜在病因。必须筛查隐球菌病的其他病灶，如中枢神经系统病灶。在资源稀缺的情况下，真菌学检查对诊断非常重要。
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