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神经脑膜隐球菌病并发IgA-λ多发性骨髓瘤

Neuromeningeal cryptoccocosis revealing IgA-λ multiple myeloma.

作者信息

Mtibaa Latifa, Beji Imen, Ayoub Manel, Baccouchi Nawel, Hannechi Souha, Aouni Zied, Abid Rym, Mazigh Chakib, Battikh Riadh, Jemli Boutheina

机构信息

Laboratory of Parasitology-Mycology, Military Hospital of Tunis, 1008, Monfleury, Tunis, Tunisia.

Department of Infectious Diseases, Military Hospital of Tunis, 1008, Monfleury, Tunis, Tunisia.

出版信息

Med Mycol Case Rep. 2021 Feb 23;32:30-33. doi: 10.1016/j.mmcr.2021.02.005. eCollection 2021 Jun.

Abstract

Cryptococcosis is an opportunistic fungal infection that is commonly associated with an immune-compromised state. Cases of cryptococcosis have rarely been reported in patients with multiple myeloma (MM). However, cryptococcosis as a presenting symptom of MM has never been reported. We presented here a case of neuromeningeal cryptococcosis in a patient without underlying diseases, who has revealed IgA-λ MM. Early detection and treatment of cryptococcosis are essential to reduce morbidity.

摘要

隐球菌病是一种机会性真菌感染,通常与免疫功能低下状态相关。多发性骨髓瘤(MM)患者中很少有隐球菌病的病例报道。然而,隐球菌病作为MM的首发症状从未被报道过。我们在此报告一例无基础疾病的患者发生神经脑膜隐球菌病,该患者已确诊为IgA-λ型MM。隐球菌病的早期检测和治疗对于降低发病率至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29e6/7932882/bcb686669ee6/gr1.jpg

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