Saoud Tarek Mohamed A, Zaazou Ashraf, Nabil Ahmed, Moussa Sybel, Lin Louis M, Gibbs Jennifer L
Faculty of Dentistry, Department of Endodontics, University of Benghazi, Benghazi, Libya.
Faculty of Dentistry, Department of Endodontics, Alexandria University, Alexandria, Egypt.
J Endod. 2014 Dec;40(12):1946-52. doi: 10.1016/j.joen.2014.08.023. Epub 2014 Oct 16.
Revascularization treatment is rapidly becoming an accepted treatment alternative for the management of endodontic pathology in immature permanent teeth with necrotic dental pulps. However, the success and timing of clinical resolution of symptoms, and radiographic outcomes of interest, such as continued hard tissue deposition within the root, are largely unknown.
In this prospective cohort study, 20 teeth were treated with a standardized revascularization treatment protocol and monitored for clinical and radiographic changes for 1 year. Standardized radiographs were collected at regular intervals, and radiographic changes were quantified.
All 20 treated teeth survived during the 12-month follow-up period, and all 20 also met the clinical criteria for success at 12 months. As a group, the treated teeth showed a statistically significant increase in radiographic root width and length and a decrease in apical diameter, although the changes in many cases were quite small (such that the clinical significance is unclear). The within-case percent change in apical diameter after 3 months was 16% and had increased to 79% by 12 months, with 55% (11/20) showing complete apical closure. The within-case percent change in root length averaged less than 1% at 3 months and increased to 5% at 12 months. The within-case percent change in root thickness averaged 3% at 3 months and 21% at 12 months.
Although clinical success was highly predictable with this procedure, clinically meaningful radiographic root thickening and lengthening are less predictable after 1-year of follow-up. Apical closure is the most consistent radiographic finding.
对于患有牙髓坏死的年轻恒牙,血管再生治疗正迅速成为一种被认可的牙髓病治疗替代方法。然而,症状临床缓解的成功与否及时间,以及诸如牙根内持续硬组织沉积等感兴趣的影像学结果,在很大程度上尚不清楚。
在这项前瞻性队列研究中,对20颗牙齿采用标准化的血管再生治疗方案进行治疗,并对其临床和影像学变化进行了1年的监测。定期收集标准化的X线片,并对影像学变化进行量化。
在12个月的随访期内,所有20颗接受治疗的牙齿均存活,并且所有20颗牙齿在12个月时也均达到了成功的临床标准。作为一个整体,接受治疗的牙齿在影像学上显示牙根宽度和长度有统计学意义的增加,根尖直径减小,尽管在许多情况下变化很小(因此临床意义尚不清楚)。3个月后根尖直径的病例内百分比变化为16%,到12个月时增加到79%,其中55%(11/20)显示根尖完全闭合。3个月时牙根长度的病例内百分比变化平均小于1%,12个月时增加到5%。3个月时牙根厚度的病例内百分比变化平均为3%,12个月时为21%。
尽管该治疗方法临床成功率高,但随访1年后,临床上有意义的牙根增厚和延长在影像学上较难预测。根尖闭合是最一致的影像学表现。