Hundt Natalie E, Amspoker Amber B, Kraus-Schuman Cynthia, Cully Jeffrey A, Rhoades Howard, Kunik Mark E, Stanley Melinda A
Houston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey VA Medical Center, Houston, TX, United States; Baylor College of Medicine, Houston, TX, United States; South Central Mental Illness Research, Education and Clinical Center (A Virtual Center).
Houston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey VA Medical Center, Houston, TX, United States; Baylor College of Medicine, Houston, TX, United States; Michael E. DeBakey VA Medical Center, Houston, TX, United States.
J Anxiety Disord. 2014 Dec;28(8):845-50. doi: 10.1016/j.janxdis.2014.09.012. Epub 2014 Oct 5.
The current study is a secondary analysis of data from a randomized controlled trial of CBT for late-life GAD (Stanley et al., 2014) which provided an opportunity to examine predictors of outcome among those who received CBT. Participants were 150 older adults who were randomized to receive 10 sessions of CBT. Completer analyses found that homework completion, number of sessions attended, lower worry severity, lower depression severity, and recruitment site predicted 6-month worry outcome on the PSWQ-A, whereas homework completion, credibility of the therapy, lower anxiety severity, and site predicted 6-month anxiety outcome on the STAI-T. In intent-to-treat multivariate analyses, however, only initial worry and anxiety severity, site, and number of sessions completed predicted treatment outcome. These results are largely consistent with predictors of outcome in younger adults and suggest that lower initial symptom severity and variables consistent with greater engagement in treatment predict outcome.
本研究是对一项针对老年广泛性焦虑障碍的认知行为疗法随机对照试验（斯坦利等人，2014年）数据的二次分析，该试验提供了一个机会来检验接受认知行为疗法者的治疗结果预测因素。参与者为150名老年人，他们被随机分配接受10次认知行为疗法治疗。完成者分析发现，家庭作业完成情况、参加治疗的次数、较低的担忧严重程度、较低的抑郁严重程度以及招募地点可预测PSWQ-A量表上6个月时的担忧结果，而家庭作业完成情况、治疗可信度、较低的焦虑严重程度以及地点可预测STAI-T量表上6个月时的焦虑结果。然而，在意向性治疗多变量分析中，只有初始担忧和焦虑严重程度、地点以及完成的治疗次数可预测治疗结果。这些结果在很大程度上与年轻成年人的治疗结果预测因素一致，表明较低的初始症状严重程度以及与更多参与治疗相关的变量可预测治疗结果。
