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电视辅助胸腔镜手术与开胸手术治疗胸部创伤的比较:系统评价与Meta分析

A comparison of video-assisted thoracoscopic surgery with open thoracotomy for the management of chest trauma: a systematic review and meta-analysis.

作者信息

Wu Na, Wu Long, Qiu Chongying, Yu Zubin, Xiang Ying, Wang Minghao, Jiang Jun, Li Yafei

机构信息

Department of Epidemiology, College of Preventive Medicine, Third Military Medical University, Chongqing, 400038, People's Republic of China,

出版信息

World J Surg. 2015 Apr;39(4):940-52. doi: 10.1007/s00268-014-2900-9.

Abstract

BACKGROUND

This study aimed to systematically review and compare the perioperative outcomes of video-assisted thoracoscopy (VATS) with open thoracotomy for chest trauma patients.

METHODS

We conducted a systematic review and meta-analysis of randomized control trials and cohort studies comparing the perioperative outcomes of VATS with open thoracotomy for chest trauma patients. Clinical endpoints included postoperative complications, perioperative mortality rate, chest tube drainage volume, duration of tube drainage, duration of hospitalization, operation time, and amount of bleeding and transfusion volume in operation. A subgroup analysis was performed to explore the potential source of heterogeneity.

RESULTS

Twenty-six studies were included. Pooled analyses showed significant reductions in the incidence of postoperative complications (risk ratio [RR] [95% confidence interval (CI)], 0.47 [0.35, 0.64]), chest tube drainage volume (mean difference [MD] [95% CI], -146.88 ml [-196.04, -97.72]), duration of tube drainage (MD, -1.71 days; 95% CI -2.16 to -1.26), duration of hospitalization (MD, -4.67 days; 95% CI -5.19 to-4.14), operation time (MD, -41.18 min; 95% CI -52.85 to -29.51), and amount of bleeding (MD, -119.10 ml; 95% CI -147.28 to -90.92) and transfusion volume (MD, -379.51 ml; 95% CI -521.24 to-237.77) in chest trauma patients treated with VATS compared with open thoracotomy. The perioperative mortality rate was not significantly different between patients received VATS and open thoracotomy (RR, 0.52; 95% CI 0.22-1.21).

CONCLUSIONS

Compared to open thoracotomy, VATS is an effective and even better treatment for improving perioperative outcomes of hemodynamically stable patients with chest trauma and reduce the complications. However, caution should also be exercised in certain clinical scenarios.

摘要

背景

本研究旨在系统评价和比较电视辅助胸腔镜手术(VATS)与开胸手术治疗胸部创伤患者的围手术期结局。

方法

我们对比较VATS与开胸手术治疗胸部创伤患者围手术期结局的随机对照试验和队列研究进行了系统评价和荟萃分析。临床终点包括术后并发症、围手术期死亡率、胸腔闭式引流量、引流时间、住院时间、手术时间、术中出血量和输血量。进行亚组分析以探讨异质性的潜在来源。

结果

纳入26项研究。汇总分析显示,与开胸手术相比,VATS治疗胸部创伤患者术后并发症发生率(风险比[RR][95%置信区间(CI)],0.47[0.35,0.64])、胸腔闭式引流量(平均差[MD][95%CI],-146.88ml[-196.04,-97.72])、引流时间(MD,-1.71天;95%CI-2.16至-1.26)、住院时间(MD,-4.67天;95%CI-5.19至-4.14)、手术时间(MD,-41.18分钟;95%CI-52.85至-29.51)、术中出血量(MD,-119.10ml;95%CI-147.28至-90.92)和输血量(MD,-379.51ml;95%CI-521.24至-237.77)均显著降低。接受VATS和开胸手术的患者围手术期死亡率无显著差异(RR,0.52;95%CI0.22-1.21)。

结论

与开胸手术相比,VATS是改善血流动力学稳定的胸部创伤患者围手术期结局和减少并发症的一种有效甚至更好的治疗方法。然而,在某些临床情况下也应谨慎使用。

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