新生儿病房中婴儿被益生菌生物体交叉定植的情况。
Cross-colonization of infants with probiotic organisms in a neonatal unit.
作者信息
Hickey L, Garland S M, Jacobs S E, O'Donnell C P F, Tabrizi S N
机构信息
Department of Neonatal Medicine, Royal Children's Hospital, Parkville, Victoria, Australia; School of Medicine & Medical Science, University College Dublin, Ireland; Neonatal Services, Royal Women's Hospital, Parkville, Victoria, Australia.
The Women's Centre for Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia; Department of Microbiology, Royal Children's Hospital, Parkville, Victoria, Australia; Infection and Immunity Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.
出版信息
J Hosp Infect. 2014 Dec;88(4):226-9. doi: 10.1016/j.jhin.2014.09.006. Epub 2014 Oct 2.
This study aimed to assess probiotic cross-colonization between infants in a neonatal unit where probiotics were being administered to preterm infants during a clinical trial. We tested stool samples from all infants present in the unit at two time points; the first was during the trial and the second was after trial completion. Samples from 43 infants were tested during the trial; all five infants receiving probiotics and three of 38 not receiving probiotics were colonized. Only one of 44 infants tested after the trial was colonized. The rate of cross-colonization was lower than in previous probiotic studies.
本研究旨在评估在一项临床试验中对早产儿施用益生菌的新生儿重症监护病房内婴儿之间的益生菌交叉定殖情况。我们在两个时间点检测了该病房内所有婴儿的粪便样本；第一个时间点是在试验期间，第二个时间点是在试验结束后。试验期间对43名婴儿的样本进行了检测；接受益生菌的5名婴儿以及未接受益生菌的38名婴儿中的3名被定殖。试验结束后检测的44名婴儿中只有1名被定殖。交叉定殖率低于之前的益生菌研究。
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