Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Addiction Research Center, National Cheng Kung University, Tainan, Taiwan.
Eur Psychiatry. 2015 Feb;30(2):193-7. doi: 10.1016/j.eurpsy.2014.09.001. Epub 2014 Oct 28.
This study was performed to investigate the association between the mid-brain serotonin transporter (SERT) availability and intelligence quotient (IQ).
One hundred and thirteen healthy participants, including 52 male and 61 female subjects, were recruited. We used SPECT with [(123)I]ADAM images to determine the SERT availability in the mid-brain, and measured the subjects' IQ using the WAIS-R.
We found a significant positive correlation between the mid-brain SERT availability and the IQ of the participants. Even when controlling for age and sex, the significant association still existed.
This result implied that the higher the SERT binding in the mid-brain, the better the IQ in healthy participants.
本研究旨在探讨中脑 5-羟色胺转运体（SERT）的可用性与智商（IQ）之间的关系。
本研究共招募了 113 名健康参与者，其中包括 52 名男性和 61 名女性。我们使用 SPECT 和 [(123)I]ADAM 图像来确定中脑 SERT 的可用性，并使用 WAIS-R 测量参与者的 IQ。
我们发现中脑 SERT 的可用性与参与者的 IQ 呈显著正相关。即使在控制年龄和性别后，这种显著关联仍然存在。
这一结果表明，在健康参与者中，中脑 SERT 结合越高，IQ 越高。
