Marks K E, Bauer T W
Department of Orthopedic Surgery, Cleveland Clinic Foundation, Ohio.
Orthop Clin North Am. 1989 Jul;20(3):377-93.
Benign and malignant fibrous tumors of bone are some of the most common tumors encountered by the orthopedic surgeon. Fibrous dysplasia, fibrous cortical defect, non-ossifying fibroma, benign fibrous histiocytoma and osteofibrous dysplasia are benign tumors best treated conservatively or by intralesional/marginal excision. Desmoplastic fibromas are locally aggressive and require a wide margin for surgical cure. Malignant fibrous histiocytoma and fibrosarcoma of bone are malignant bone tumors and must be treated with wide/radical margins and for malignant fibrous histiocytoma adjunctive chemotherapy.
骨的良性和恶性纤维性肿瘤是骨科医生最常遇到的一些肿瘤。纤维发育不良、纤维皮质缺损、非骨化性纤维瘤、良性纤维组织细胞瘤和骨纤维发育不良是良性肿瘤,最好采用保守治疗或病损内/边缘切除治疗。促结缔组织增生性纤维瘤具有局部侵袭性,手术治愈需要广泛切除边缘。骨恶性纤维组织细胞瘤和纤维肉瘤是恶性骨肿瘤,必须采用广泛/根治性切除边缘进行治疗,对于恶性纤维组织细胞瘤还需辅助化疗。