Bujňáková Zdenka, Dutková Erika, Baláž Matej, Turianicová Erika, Baláž Peter
Institute of Geotechnics, Slovak Academy of Sciences, Watsonova 45, Košice 040 01, Slovakia.
Institute of Geotechnics, Slovak Academy of Sciences, Watsonova 45, Košice 040 01, Slovakia.
Int J Pharm. 2015 Jan 15;478(1):187-192. doi: 10.1016/j.ijpharm.2014.11.043. Epub 2014 Nov 18.
In this paper the stability of the arsenic sulfide (As4S4) nanosuspension prepared by wet milling in a circulation mill in the environment of copolymer Poloxamer 407 was studied. The obtained As4S4 particles in nanosuspension were of ∼ 100 nm in size. The influence of temperature and UV irradiation on the changes in physical and/or chemical properties was followed. Long-term stability was observed via particle size distribution and zeta potential measurements. Influence of UV irradiation was studied via UV-vis spectroscopy (UV-vis), photoluminicsence (PL) technique and Fourier transform infrared spectroscopy (FTIR) measurements. The best stability of the nanosuspension (24 weeks) was achieved when stored at 4°C and in the dark.
本文研究了在共聚物泊洛沙姆407环境下，通过循环研磨机湿磨制备的硫化砷（As4S4）纳米悬浮液的稳定性。纳米悬浮液中获得的As4S4颗粒尺寸约为100 nm。跟踪了温度和紫外线照射对物理和/或化学性质变化的影响。通过粒度分布和zeta电位测量观察长期稳定性。通过紫外可见光谱（UV-vis）、光致发光（PL）技术和傅里叶变换红外光谱（FTIR）测量研究紫外线照射的影响。当纳米悬浮液在4°C且黑暗中储存时，可实现最佳稳定性（24周）。
