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一种用于水中铅检测的仿生传感器。

A biomimetic sensor for the detection of lead in water.

机构信息

School of Life and Environmental Sciences, Deakin University, Vic. 3217, Australia.

School of Life and Environmental Sciences, Deakin University, Vic. 3217, Australia; College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, China.

出版信息

Biosens Bioelectron. 2015 May 15;67:621-4. doi: 10.1016/j.bios.2014.09.077. Epub 2014 Oct 2.

Abstract

The monitoring of lead (II) ions (Pb(2+)) in water is essential for both human health and the environment. Herein, a simple yet innovative biosensor for Pb(2+) detection is presented. The sensor is developed by the self-assembly of gold nanoparticles (GNPs) core-satellite structure using naturally occurring tripeptide glutathione (GSH) as linker. The addition of Pb(2+) caused a red-to-blue color change and the localized surface plasmon resonance (LSPR) band was shifted to ca. 650 nm. The limit of detection (LOD) is found to be 47.6 nM (9.9 ppb) by UV-vis spectroscopy with high selectivity against other heavy metals. This method offers a new strategy for heavy metal detection using functionalized GNPs.

摘要

水中铅(II)离子(Pb(2+))的监测对人类健康和环境都至关重要。在此,我们提出了一种简单而创新的用于 Pb(2+)检测的生物传感器。该传感器是通过使用天然三肽谷胱甘肽(GSH)作为连接物,自组装金纳米粒子(GNPs)核-卫星结构而开发的。加入 Pb(2+)后,会发生红-蓝颜色变化,局域表面等离子体共振(LSPR)带移至约 650nm。通过紫外-可见光谱法发现,该方法对其他重金属具有高选择性,LOD 为 47.6 nM(9.9 ppb)。该方法为使用功能化 GNPs 进行重金属检测提供了一种新策略。

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