Jeong H J, Park K H, Choi H K, Kim K H, Choi I J
Yonsei Med J. 1989;30(1):88-94. doi: 10.3349/ymj.1989.30.1.88.
A case of Wilms' tumor in a 67 year-old female is presented. The tumor totally replaced the left kidney with extension to Gerota's fascia, the adrenal gland and ureter, with tumor thrombi in the left renal vein. Multiple bony metastases to the skull, shoulder, rib, ilium, acetabulum and femur were noted also. Microscopically, the tumor was composed predominantly of blastemal tissue with diffuse anaplasia with areas of tubular differentiation and chondroid elements. Clear cell nests were found in the proximal ureter with gradual maturation downward.
本文报告一例67岁女性的肾母细胞瘤病例。肿瘤完全取代了左肾,并延伸至肾周筋膜、肾上腺和输尿管,左肾静脉内有瘤栓形成。同时还发现颅骨、肩部、肋骨、髂骨、髋臼和股骨有多处骨转移。显微镜下,肿瘤主要由母细胞组织构成,伴有弥漫性间变,可见管状分化区域和软骨样成分。在近端输尿管发现透明细胞巢,并向下逐渐成熟。