The TM6SF2 variants, novel genetic predictors for nonalcoholic steatohepatitis.
作者信息
Roh Yoon-Seok, Loomba Rohit, Seki Ekihiro
机构信息
Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla, California.
出版信息
Gastroenterology. 2015 Jan;148(1):252-4. doi: 10.1053/j.gastro.2014.11.014. Epub 2014 Nov 18.
Abstract
摘要
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本文引用的文献
1
TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.TM6SF2基因的rs58542926位点影响非酒精性脂肪性肝病患者肝纤维化的进展。
Nat Commun. 2014 Jun 30;5:4309. doi: 10.1038/ncomms5309.
2
TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.TM6SF2 是肝脏脂肪代谢的调节因子，影响甘油三酯的分泌和肝内脂滴含量。
Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8913-8. doi: 10.1073/pnas.1323785111. Epub 2014 Jun 4.
3
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease.外显子组关联研究鉴定出一个 TM6SF2 变异，该变异赋予非酒精性脂肪性肝病易感性。
Nat Genet. 2014 Apr;46(4):352-6. doi: 10.1038/ng.2901. Epub 2014 Feb 16.
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