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商业综合交付系统中美洲印第安人和阿拉斯加原住民的糖尿病护理和结局:一项糖尿病监测、预防和管理(SUPREME-DM)研究。

Diabetes care and outcomes for American Indians and Alaska natives in commercial integrated delivery systems: a SUrveillance, PREvention, and ManagEment of Diabetes Mellitus (SUPREME-DM) Study.

机构信息

Division of Research , Kaiser Permanente Northern California , Oakland, California , USA.

Institute for Health Research, Kaiser Permanente Colorado , Denver, Colorado , USA.

出版信息

BMJ Open Diabetes Res Care. 2014 Nov 17;2(1):e000043. doi: 10.1136/bmjdrc-2014-000043. eCollection 2014.

DOI:10.1136/bmjdrc-2014-000043
PMID:25452877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4246918/
Abstract

OBJECTIVE

To compare cardiovascular disease risk factor testing rates and intermediate outcomes of care between American Indian/Alaska Native (AI/AN) patients with diabetes and non-Hispanic Caucasians enrolled in nine commercial integrated delivery systems in the USA.

RESEARCH DESIGN AND METHODS

We used modified Poisson regression models to compare the annual testing rates and risk factor control levels for glycated haemoglobin (HbA1c), low-density lipoprotein cholesterol (LDL-C), and systolic blood pressure (SBP); number of unique diabetes drug classes; insulin use; and oral diabetes drug medication adherence between insured AI/AN and non-Hispanic white adults with diabetes aged ≥18 in 2011.

RESULTS

5831 AI/AN patients (1.8% of the cohort) met inclusion criteria. After adjusting for age, gender, comorbidities, insulin use, and geocoded socioeconomic status, AI/AN patients had similar rates of annual HbA1c, LDL-C, and SBP testing, and LDL-C and SBP control, compared with non-Hispanic Caucasians. However, AI/AN patients were significantly more likely to have HbA1c >9% (>74.9 mmol/mol; RR=1.47, 95% CI 1.38 to 1.58), and significantly less likely to adhere to their oral diabetes medications (RR=0.90, 95% CI 0.88 to 0.93) compared with non-Hispanic Caucasians.

CONCLUSIONS

AI/AN patients in commercial integrated delivery systems have similar blood pressure and cholesterol testing and control, but significantly lower rates of HbA1c control and diabetes medication adherence, compared with non-Hispanic Caucasians. As more AI/ANs move to urban and suburban settings, clinicians and health plans should focus on addressing disparities in diabetes care and outcomes in this population.

摘要

目的

比较美国九家商业综合医疗服务系统中患有糖尿病的美国印第安人/阿拉斯加原住民(AI/AN)患者与非西班牙裔白种人之间心血管疾病风险因素检测率和中间护理结果。

研究设计和方法

我们使用修正泊松回归模型比较了 2011 年参保的年龄≥18 岁的 AI/AN 和非西班牙裔白种糖尿病患者的年度糖化血红蛋白(HbA1c)、低密度脂蛋白胆固醇(LDL-C)和收缩压(SBP)检测率和风险因素控制水平、独特的糖尿病药物种类数、胰岛素使用情况以及口服糖尿病药物的用药依从性。

结果

5831 名 AI/AN 患者(队列的 1.8%)符合纳入标准。在调整年龄、性别、合并症、胰岛素使用和地理编码的社会经济地位后,与非西班牙裔白种人相比,AI/AN 患者的年度 HbA1c、LDL-C 和 SBP 检测率以及 LDL-C 和 SBP 控制率相似。然而,与非西班牙裔白种人相比,AI/AN 患者的 HbA1c>9%(>74.9mmol/mol;RR=1.47,95%CI 1.38 至 1.58)的可能性显著更高,且他们对口服糖尿病药物的依从性显著更低(RR=0.90,95%CI 0.88 至 0.93)。

结论

与非西班牙裔白种人相比,商业综合医疗服务系统中的 AI/AN 患者的血压和胆固醇检测和控制情况相似,但 HbA1c 控制和糖尿病药物依从率显著更低。随着越来越多的 AI/AN 人迁往城市和郊区,临床医生和医疗保健计划应重点解决这一人群中糖尿病护理和结果的差异。