人类免疫缺陷病毒暴露前预防：过去、现在与未来
Pre-exposure prophylaxis for human immunodeficiency virus: the past, present, and future.
作者信息
Castel Amanda D, Magnus Manya, Greenberg Alan E
机构信息
Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Avenue, Northwest, 5th Floor, Washington, DC 20052, USA.
Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Avenue, Northwest, 5th Floor, Washington, DC 20052, USA.
出版信息
Infect Dis Clin North Am. 2014 Dec;28(4):563-83. doi: 10.1016/j.idc.2014.08.001. Epub 2014 Nov 20.
This article presents an overview of pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) prevention. The authors describe the past animal and human research that has been conducted that informs our current understanding of PrEP; summarize ongoing research in the area, including describing new regimens and delivery mechanisms being studied for PrEP; and highlight key issues that must be addressed in order to implement and optimize the use of this HIV prevention tool.
本文概述了用于预防人类免疫缺陷病毒（HIV）的暴露前预防（PrEP）。作者描述了过去进行的动物和人体研究，这些研究为我们当前对PrEP的理解提供了依据；总结了该领域正在进行的研究，包括描述正在研究的用于PrEP的新方案和给药机制；并强调了为实施和优化这种HIV预防工具的使用而必须解决的关键问题。
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