Rask Mette T, Rosendal Marianne, Fenger-Grøn Morten, Bro Flemming, Ørnbøl Eva, Fink Per
Research Unit for General Practice, Section for General Medical Practice, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark.
Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Barthsgade 5, 8200 Aarhus N, Denmark.
Gen Hosp Psychiatry. 2015 Jan-Feb;37(1):53-9. doi: 10.1016/j.genhosppsych.2014.10.007. Epub 2014 Oct 22.
The objective was to explore patient characteristics and 10-year outcome of sick leave and work disability for patients with recent-onset multiple medically unexplained symptoms (MUS) and persistent somatoform disorders (SD).
Consecutive patients consulting their family physician (FP) completed a preconsultation questionnaire on symptoms and mental illness (n=1785). The main problem was categorized by the FP after the consultation, and a stratified subsample was examined using a standardized diagnostic interview (n=701). Patients were grouped into three cohorts: recent onset of multiple MUS (n=84); Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, persistent SD (n=183); and reference group with well-defined physical disease according to FP (n=833). Register data on sick leave and disability pension were obtained.
At index consultation, disability pension was received by 8.3% (n=7) in the recent-onset multiple MUS group, 19.1% (n=35) in the SD group and 3.5% (n=29) in the reference group. Both the recent-onset multiple MUS group [hazard ratio (HR)=2.28, 95% confidence interval (CI): 1.14-4.55] and the SD group (HR=3.26, 95% CI:1.93-5.51) had increased risk of new disability pension awards. Furthermore, the SD group had increased risk of sick leave.
Both recent-onset and persistent MUS have significant long-term impact on patient functioning in regard to working life; this calls for early recognition and adequate management of MUS in primary care.
探讨近期出现多种医学上无法解释的症状(MUS)和持续性躯体形式障碍(SD)患者的特征以及病假和工作残疾的10年结局。
连续向家庭医生(FP)咨询的患者完成了一份关于症状和精神疾病的咨询前问卷(n = 1785)。咨询后,FP对主要问题进行分类,并使用标准化诊断访谈对分层子样本进行检查(n = 701)。患者被分为三组队列:近期出现多种MUS(n = 84);《精神障碍诊断与统计手册》第四版,持续性SD(n = 183);以及根据FP诊断为明确躯体疾病的参照组(n = 833)。获取了病假和残疾抚恤金的登记数据。
在首次咨询时,近期出现多种MUS组中8.3%(n = 7)的患者领取了残疾抚恤金,SD组中为19.1%(n = 35),参照组中为3.5%(n = 29)。近期出现多种MUS组[风险比(HR)= 2.28,95%置信区间(CI):1.14 - 4.55]和SD组(HR = 3.26,95% CI:1.93 - 5.51)获得新残疾抚恤金的风险均增加。此外,SD组病假风险增加。
近期出现的和持续性的MUS在工作生活方面对患者功能均有显著的长期影响;这就要求在初级保健中对MUS进行早期识别和适当管理。