Department of Neurology, Baylor College of Medicine, 2002 Holcombe Boulevard, Houston, TX 77030, USA.
Neuron. 2014 Nov 19;84(4):658-9. doi: 10.1016/j.neuron.2014.11.001.
Dementia is among the most feared complications of aging in the U.S. In this issue of Neuron, Yamazaki et al. (2014) present a tour de force mechanistic analysis of a "hit" from a proteomic screen carried out using a Drosophila mutation that affects memory.
痴呆症是美国老年人最担心的并发症之一。在本期《神经元》杂志上,Yamazaki 等人(2014 年)展示了一项使用影响记忆的果蝇突变进行蛋白质组筛选的“命中”的强大机制分析。