Department of Surgery, Canisius Wilhelmina Hospital, Postbus 9015, 6500 GS Nijmegen, The Netherlands.
Medical Oncology, Academic Medical Center, University of Amsterdam, Postbus 22660, 1100 DD Amsterdam, The Netherlands.
Crit Rev Oncol Hematol. 2015 Feb;93(2):116-26. doi: 10.1016/j.critrevonc.2014.09.003. Epub 2014 Oct 16.
Inflammatory breast cancer (IBC) is the most aggressive entity of breast cancer. Management involves coordination of multidisciplinary management and usually includes neoadjuvant chemotherapy, ablative surgery if a tumor-free resection margin is expected and locoregional radiotherapy. This multimodal therapeutic approach has significantly improved patient survival. However, the median overall survival among women with IBC is still poor. By elucidating the biologic characteristics of IBC, new treatment options may become available. We performed a comprehensive review of the English-language literature on IBC through computerized literature searches. The objective of the current review is to present an overview of the literature related to the biology, imaging and multidisciplinary treatment of inflammatory breast cancer.
炎性乳腺癌（IBC）是乳腺癌中最具侵袭性的实体瘤。其治疗包括多学科治疗的协调，通常包括新辅助化疗、如果预计可以获得无肿瘤切缘则进行根治性手术，以及局部区域放疗。这种多模式治疗方法显著提高了患者的生存率。然而，IBC 患者的中位总生存期仍然较差。通过阐明 IBC 的生物学特征，可能会出现新的治疗选择。我们通过计算机文献检索对 IBC 的英文文献进行了全面综述。目前综述的目的是概述与炎性乳腺癌的生物学、影像学和多学科治疗相关的文献。
