Yu Chao, Jin Yinghua, Zhang Wei
Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO, 80309, USA.
Chem Rec. 2015 Feb;15(1):97-106. doi: 10.1002/tcr.201402076. Epub 2014 Dec 2.
Shape-persistent host molecules that are constructed solely through covalent bonds have been extensively investigated as alternatives to supramolecular architectures, which have shown interesting applications such as guest encapsulation and release, catalysis, and molecular recognition. Similar to the supramolecular self-assembly process, recent rapid development of dynamic covalent chemistry has enabled the covalent assembly of complex organic molecules that exhibit a finite cavity of well-defined shape and size. Alkyne metathesis represents an emerging dynamic covalent reaction, which provides rigid and linear acetylene linkages. In this account, we describe the dynamic assembly of shape-persistent arylene ethynylene cages with various shapes and sizes through one-step alkyne metathesis. The controlled cage-fullerene binding and the potential application of these cages in fullerene purification are also discussed.
仅通过共价键构建的形状持久主体分子作为超分子结构的替代物已被广泛研究，超分子结构已显示出有趣的应用，如客体包封与释放、催化和分子识别。与超分子自组装过程类似，动态共价化学最近的快速发展使得能够共价组装具有明确形状和尺寸的有限空腔的复杂有机分子。炔烃复分解代表一种新兴的动态共价反应，它提供刚性和线性乙炔连接。在本报告中，我们描述了通过一步炔烃复分解动态组装各种形状和尺寸的形状持久亚芳基乙炔笼。还讨论了这些笼与富勒烯的可控结合及其在富勒烯纯化中的潜在应用。
