• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

矮小症的治疗方法。

Approach to short stature.

作者信息

Yadav Sangeeta, Dabas Aashima

机构信息

Department of Pediatrics, Pediatric and Adolescent Endocrinology Unit, Maulana Azad Medical College, University of Delhi, New Delhi, India,

出版信息

Indian J Pediatr. 2015 May;82(5):462-70. doi: 10.1007/s12098-014-1609-y. Epub 2014 Dec 4.

DOI:10.1007/s12098-014-1609-y
PMID:25465677
Abstract

Growth is an essential and continuous process in animate objects. Linear growth or height is considered synonymous to growth by most children and their parents. Any disturbance or faltering in height is thus, a frequent cause of concern for the family. The foremost responsibility of the clinician is to detect whether the growth pattern is appropriate or deviant from the normal. A detailed clinical evaluation including accurate anthropometry is essential to suspect and diagnose the underlying cause. The role of more sophisticated investigations is reserved for fewer children who are pathologically short. Treatment is directed as per the primary etiology of short stature. Growth hormone therapy is a highly specific and targeted therapy which should be instituted only under expert consultation.

摘要

生长是生物体内一个基本且持续的过程。大多数儿童及其家长认为线性生长或身高增长等同于生长。因此,身高方面的任何干扰或生长迟缓都是家庭频繁担忧的原因。临床医生的首要职责是检测生长模式是否正常或偏离正常。包括准确人体测量学在内的详细临床评估对于怀疑和诊断潜在病因至关重要。更复杂检查的作用仅适用于少数病理性身材矮小的儿童。治疗是根据身材矮小的主要病因进行的。生长激素疗法是一种高度特异性和针对性的疗法,仅应在专家咨询后实施。

相似文献

1
Approach to short stature.矮小症的治疗方法。
Indian J Pediatr. 2015 May;82(5):462-70. doi: 10.1007/s12098-014-1609-y. Epub 2014 Dec 4.
2
[Idiopathic short stature and treatment with biosynthetic growth hormone: clinical and ethical reflections on an arbitrary diagnosis].[特发性身材矮小与生物合成生长激素治疗:关于一种任意诊断的临床与伦理思考]
An Pediatr (Barc). 2012 Feb;76(2):53-7. doi: 10.1016/j.anpedi.2011.10.009. Epub 2011 Dec 19.
3
Debate: idiopathic short stature should be treated with growth hormone.辩论:特发性身材矮小是否应该用生长激素治疗。
J Paediatr Child Health. 2013 Mar;49(3):165-9. doi: 10.1111/j.1440-1754.2012.02465.x. Epub 2012 May 15.
4
Growth hormone in children with idiopathic short stature.特发性身材矮小儿童的生长激素
BMJ. 2011 Mar 14;342:d1248. doi: 10.1136/bmj.d1248.
5
Initiation of growth hormone therapy in idiopathic short stature: do gender differences exist?特发性身材矮小患者生长激素治疗的起始:存在性别差异吗?
J Pediatr Endocrinol Metab. 2015 Jan;28(1-2):101-4. doi: 10.1515/jpem-2014-0003.
6
Parent requests growth hormone for child with idiopathic short stature.家长为患有特发性身材矮小的孩子申请生长激素。
J Dev Behav Pediatr. 2004 Oct;25(5 Suppl):S79-83. doi: 10.1097/00004703-200410001-00016.
7
Medically underserved girls receive less evaluation for short stature.医疗资源不足地区的女孩在身材矮小方面接受的评估较少。
Pediatrics. 2011 Apr;127(4):696-702. doi: 10.1542/peds.2010-1563. Epub 2011 Mar 21.
8
[Hormone treatment for short statured children? For a critical approach to sociocultural norms about short stature].[激素治疗身材矮小的儿童?对有关身材矮小的社会文化规范的批判性探讨]
Med Sci (Paris). 2019 Nov;35(11):891-895. doi: 10.1051/medsci/2019173. Epub 2019 Dec 17.
9
Dose-dependent effect of growth hormone on final height in children with short stature without growth hormone deficiency.生长激素对无生长激素缺乏的矮小儿童最终身高的剂量依赖性效应
J Clin Endocrinol Metab. 2008 Nov;93(11):4342-50. doi: 10.1210/jc.2008-0707. Epub 2008 Aug 26.
10
Height outcome of short children with hypochondroplasia after recombinant human growth hormone treatment: a meta-analysis.重组人生长激素治疗后软骨发育不全矮小儿童的身高结局:一项荟萃分析。
Pharmacogenomics. 2015 Nov;16(17):1965-73. doi: 10.2217/pgs.15.129. Epub 2015 Nov 10.

引用本文的文献

1
Short stature in pre-pubertal children with X-linked hypophosphatemia.X连锁低磷血症青春期前儿童的身材矮小
Endocr Connect. 2025 May 31;14(6). doi: 10.1530/EC-24-0605. Print 2025 Jun 1.
2
Growth Outcomes and Final Height in Children with Acquired Hypothyroidism: A Systematic Review.获得性甲状腺功能减退症患儿的生长结局与最终身高:一项系统评价
Children (Basel). 2024 Dec 11;11(12):1510. doi: 10.3390/children11121510.
3
A Recurrent Mutation in Growth Hormone Receptor () Gene Underlying Laron-type Dwarfism in a Pakistani Family.

本文引用的文献

1
Crosssectional growth curves for height, weight and body mass index for affluent Indian children, 2007.2007年富裕印度儿童身高、体重和体重指数的横断面生长曲线。
Indian Pediatr. 2009 Jun;46(6):477-89.
2
Enrolment and baseline characteristics in the WHO Multicentre Growth Reference Study.世界卫生组织多中心生长参考研究中的入组情况及基线特征。
Acta Paediatr Suppl. 2006 Apr;450:7-15. doi: 10.1111/j.1651-2227.2006.tb02371.x.
3
Assessment of growth by primary health care providers.初级卫生保健提供者对生长情况的评估。
一个巴基斯坦家族中生长激素受体()基因突变导致拉伦型侏儒症。
Yale J Biol Med. 2023 Sep 29;96(3):313-325. doi: 10.59249/TCAA2040. eCollection 2023 Sep.
4
An Observational Study on Response to Growth Hormone Therapy in Indian Patients of Short Stature with Special Emphasis on Biochemical Parameters and Bone Biomarkers.一项关于印度身材矮小患者生长激素治疗反应的观察性研究,特别关注生化参数和骨生物标志物。
Indian J Endocrinol Metab. 2023 May-Jun;27(3):260-269. doi: 10.4103/ijem.ijem_303_22. Epub 2023 Jun 26.
5
Upper and Lower Body Segment Ratios from Birth to 18 years in Children from Western Maharashtra.西马哈拉施特拉邦儿童从出生到 18 岁的上下半身比例
Indian J Pediatr. 2019 Jun;86(6):503-507. doi: 10.1007/s12098-019-02883-x. Epub 2019 Feb 13.
6
Etiological factors of short stature in children and adolescents: experience at a tertiary care hospital in Egypt.儿童和青少年身材矮小的病因:埃及一家三级护理医院的经验。
Ther Adv Endocrinol Metab. 2017 May;8(5):75-80. doi: 10.1177/2042018817707464. Epub 2017 May 3.
J Pediatr Health Care. 2000 Jul-Aug;14(4):166-71. doi: 10.1067/mph.2000.104538.
4
Growth charts suitable for evaluation of Indian children.适用于评估印度儿童的生长图表。
Indian Pediatr. 1998 Sep;35(9):859-65.
5
Utah Growth Study: growth standards and the prevalence of growth hormone deficiency.犹他州生长发育研究:生长标准与生长激素缺乏症的患病率
J Pediatr. 1994 Jul;125(1):29-35. doi: 10.1016/s0022-3476(94)70117-2.
6
Physical growth in Indian affluent children (birth-6 years).印度富裕家庭儿童(出生至6岁)的身体发育情况
Indian Pediatr. 1994 Apr;31(4):377-413.
7
Causes of short stature. A community study of children in Newcastle upon Tyne.身材矮小的原因。泰恩河畔纽卡斯尔儿童的一项社区研究。
Lancet. 1974 Jan 12;1(7846):42-5. doi: 10.1016/s0140-6736(74)93041-4.
8
Short stature in Indian children: the extent of the problem.印度儿童的身材矮小问题:问题的严重程度
Indian J Pediatr. 1991 Sep-Oct;58 Suppl 1:57-8. doi: 10.1007/BF02750984.
9
Poor growth in school entrants as an index of organic disease: the Wessex growth study.入学儿童生长发育不良作为器质性疾病的一项指标:韦塞克斯生长发育研究
BMJ. 1992 Dec 5;305(6866):1400-2. doi: 10.1136/bmj.305.6866.1400.