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补充活性成分的饮食对脂质和血糖状况影响的研究。

Study of the effects of a diet supplemented with active components on lipid and glycemic profiles.

作者信息

Langella Ciro, Naviglio Daniele, Marino Marina, Gallo Monica

机构信息

Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.

Department of Chemical Sciences, University of Naples Federico II, Naples, Italy.

出版信息

Nutrition. 2015 Jan;31(1):180-6. doi: 10.1016/j.nut.2014.07.015. Epub 2014 Aug 8.

Abstract

OBJECTIVES

Currently, there are numerous studies on risk factors for cardiovascular disease and the potential for functional foods to bring benefits or improve people's health. However, most of these studies are conducted with middle-aged individuals. The aim of this study was to evaluate the effects of supplementing a typical diet with some functional components, which are substances that when consumed in small quantities can improve people's welfare.

METHODS

The participants in this study were young; slightly overweight; had normal glucose tolerance; and had lipid values indicating dyslipidemia or close dyslipidemia. Following a 4-wk run-in phase, participants followed either a diet containing foods enriched with ω-3 fatty acids, β-glucans, phytosterols, and vitamin E or an isoenergetic diet without the active components. Sixteen individuals (age range 20 to 37 y) were randomly assigned to one of two groups. At the end of treatment, while fasting, plasma concentrations of triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and total cholesterol were measured. Furthermore, blood glucose was evaluated after fasting and after a meal enriched with β-glucans.

RESULTS

There was a statistically significant reduction (α < 0.05) across the lipid profile. A meal rich in β-glucans produced a glycemic response significantly lower than the nonenriched meal.

CONCLUSION

The dietary supplements used in this work, based on the integration of functional components into the usual diet of the population, have proved effective in reducing peak levels of postprandial glucose and the risk for dyslipidemia. Therefore, these functional components proved a valuable aid in the prevention of cardiovascular diseases and metabolic disorders.

摘要

目的

目前,有许多关于心血管疾病风险因素以及功能性食品带来益处或改善人们健康潜力的研究。然而,这些研究大多是针对中年个体进行的。本研究的目的是评估在典型饮食中添加一些功能性成分的效果,这些功能性成分是少量食用时可改善人们健康状况的物质。

方法

本研究的参与者为年轻人;体重略超重;葡萄糖耐量正常;血脂值表明存在血脂异常或接近血脂异常。在为期4周的导入期之后,参与者遵循两种饮食之一,一种饮食包含富含ω-3脂肪酸、β-葡聚糖、植物甾醇和维生素E的食物,另一种是不含活性成分的等能量饮食。16名个体(年龄范围20至37岁)被随机分配到两组中的一组。在治疗结束时,空腹测量甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和总胆固醇的血浆浓度。此外,在空腹和食用富含β-葡聚糖的餐后评估血糖。

结果

血脂谱有统计学显著降低(α<0.05)。富含β-葡聚糖的一餐产生的血糖反应明显低于未强化的一餐。

结论

本研究中使用的膳食补充剂,通过将功能性成分融入人群的日常饮食中,已证明在降低餐后血糖峰值和血脂异常风险方面有效。因此,这些功能性成分被证明对预防心血管疾病和代谢紊乱有宝贵的帮助。

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