Heo Jun, Jung Min Kyu
Jun Heo, Min Kyu Jung, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu 700712, South Korea.
World J Gastroenterol. 2014 Nov 28;20(44):16721-5. doi: 10.3748/wjg.v20.i44.16721.
To evaluate the safety and efficacy of partially covered self-expandable metallic stents (SEMSs) in benign pyloric obstruction.
We retrospectively analyzed data from 10 consecutive patients with peptic ulcer-related pyloric obstructive symptoms (gastric outlet obstruction scoring system (GOOSS) score of 1) between March 2012 and September 2013. The patients were referred to and managed by partially covered SEMS insertion in our tertiary academic center. We assessed the technical success, symptom improvement, and adverse events after stenting.
Early symptoms were improved just 3 d after SEMS placement in all 10 patients. The GOOSS score of all patients improved from 1 to 3. There were no serious immediate adverse events. The overall rate of being symptom free was 90% at a median of 11 mo of follow-up (range: 4-43 mo). Five patients were managed by a rescue SEMS because of failure of previous endoscopic balloon dilatation. Among them, four patients had sustained symptom improvement after the SEMS procedure. During the follow-up period, migration of the SEMS was observed in two patients (20.0%), both of whom had previous endoscopic balloon dilatation before SEMS insertion.
Despite the small number in this study, partially covered SEMSs showed a favorable and safe outcome in the treatment of naïve benign pyloric obstruction and in salvage treatment after balloon dilatation failure.
评估部分覆膜自膨式金属支架(SEMS)治疗良性幽门梗阻的安全性和有效性。
我们回顾性分析了2012年3月至2013年9月期间连续10例患有消化性溃疡相关幽门梗阻症状(胃出口梗阻评分系统(GOOSS)评分为1)患者的数据。这些患者在我们的三级学术中心接受了部分覆膜SEMS置入治疗。我们评估了支架置入后的技术成功率、症状改善情况及不良事件。
所有10例患者在SEMS置入后3天早期症状即得到改善。所有患者的GOOSS评分从1分提高到3分。无严重的即刻不良事件。在中位随访11个月(范围:4 - 43个月)时,总体无症状率为90%。5例患者因先前内镜下球囊扩张失败而接受补救性SEMS治疗。其中,4例患者在SEMS治疗后症状持续改善。在随访期间,观察到2例患者(20.0%)的SEMS发生移位,这2例患者在SEMS置入前均曾接受过内镜下球囊扩张。
尽管本研究样本量较小,但部分覆膜SEMS在治疗初发性良性幽门梗阻及球囊扩张失败后的挽救治疗中显示出良好且安全的效果。