一种用于从全血中位点特异性捕获血细胞的新型亲水性聚合物刷图案。
A novel hydrophilic polymer-brush pattern for site-specific capture of blood cells from whole blood.
作者信息
Hou Jianwen, Shi Qiang, Ye Wei, Fan Qunfu, Shi Hengchong, Wong Shing-Chung, Xu Xiaodong, Yin Jinghua
机构信息
State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China.
出版信息
Chem Commun (Camb). 2015 Mar 11;51(20):4200-3. doi: 10.1039/c4cc09096a.
A novel hydrophilic PAMPS-PAAm brush pattern is fabricated to selectively capture blood cells from whole blood. PAMPS brushes provide antifouling surfaces to resist protein and cell adhesion while PAAm brushes effectively entrap targeted proteins for site-specific and cell-type dependent capture of blood cells.
制备了一种新型亲水性聚（2-丙烯酰胺基-2-甲基丙磺酸）-聚丙烯酰胺刷型结构，用于从全血中选择性捕获血细胞。聚（2-丙烯酰胺基-2-甲基丙磺酸）刷提供防污表面以抵抗蛋白质和细胞粘附，而聚丙烯酰胺刷有效地截留靶向蛋白质，用于血细胞的位点特异性和细胞类型依赖性捕获。
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