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社区招募的注射吸毒者中脓肿和慢性伤口的高发生率及相关危险因素。

High rates of abscesses and chronic wounds in community-recruited injection drug users and associated risk factors.

作者信息

Smith Maria Elisa, Robinowitz Natanya, Chaulk Patrick, Johnson Kristine E

机构信息

From the Department of Medicine (MES, KEJ), Division of Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, MD; and Baltimore City Health Department (NR, PC), Baltimore, MD.

出版信息

J Addict Med. 2015 Mar-Apr;9(2):87-93. doi: 10.1097/ADM.0000000000000093.

Abstract

OBJECTIVES

Abscesses and chronic wounds are common among injection drug users (IDUs) though chronic wounds have been understudied. We assessed the risk factors associated with both acute and chronic wounds within a community-based population of IDUs frequenting the Baltimore City Needle Exchange Program (BNEP).

METHODS

We performed a cross-sectional study of BNEP clients aged 18 years or more who completed an in-person survey regarding active or prior wounds including abscesses (duration <8 weeks) and chronic wounds (duration ≥8 weeks), injection practices, and skin care. Factors associated with wounds were analyzed using univariate and multivariate logistic regressions.

RESULTS

Of the 152 participants, 63.2% were men, 49.3% were white, 44.7% were African American, 34.9% had any type of current wound, 17.8% had an active abscess, and 19.7% had a current chronic wound. Abscesses were more common in women (odds ratio [OR], 2.56; 95% confidence interval [CI], 1.10-5.97) and those reporting skin-popping (OR, 5.38; 95% CI, 1.85-15.67). In a multivariate model, risk factors for an abscess included injecting with a family member/partner (adjusted OR [AOR], 4.06; 95% CI, 0.99-16.58). In a multivariable analysis of current chronic wounds, cleaning skin with alcohol before injection was protective (AOR, 0.061; 95% CI, 0.0064-0.58).

CONCLUSIONS

Abscesses and chronic wounds were prevalent among a sample of IDUs in Baltimore. Abscesses were associated with injection practices, and chronic wounds seemed linked to varying skin and tool cleaning practices. There is a pressing need for wound-related education and treatment efforts among IDUs who are at greatest risk for skin-related morbidity.

摘要

目的

脓肿和慢性伤口在注射吸毒者中很常见,不过对慢性伤口的研究较少。我们评估了巴尔的摩市针头交换项目(BNEP)中经常光顾的社区注射吸毒者人群中与急性和慢性伤口相关的风险因素。

方法

我们对年龄在18岁及以上的BNEP客户进行了一项横断面研究,这些客户完成了一项关于当前或既往伤口(包括脓肿(持续时间<8周)和慢性伤口(持续时间≥8周))、注射方式和皮肤护理的面对面调查。使用单变量和多变量逻辑回归分析与伤口相关的因素。

结果

在152名参与者中,63.2%为男性,49.3%为白人,44.7%为非裔美国人,34.9%有任何类型的当前伤口,17.8%有活动性脓肿,19.7%有当前慢性伤口。脓肿在女性中更常见(优势比[OR],2.56;95%置信区间[CI],1.10 - 5.97)以及那些报告有皮肤注射的人(OR,5.38;95%CI,1.85 - 15.67)。在多变量模型中,脓肿的风险因素包括与家庭成员/伴侣一起注射(调整后OR[AOR],4.06;95%CI,0.99 - 16.58)。在对当前慢性伤口的多变量分析中,注射前用酒精清洁皮肤具有保护作用(AOR,0.061;95%CI,0.0064 - 0.58)。

结论

脓肿和慢性伤口在巴尔的摩的注射吸毒者样本中很普遍。脓肿与注射方式有关,慢性伤口似乎与不同的皮肤和工具清洁方式有关。对于面临皮肤相关发病风险最高的注射吸毒者,迫切需要开展与伤口相关的教育和治疗工作。

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