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查尔森合并症指数可用于前瞻性地识别未来将产生高额费用的患者。

The Charlson comorbidity index can be used prospectively to identify patients who will incur high future costs.

作者信息

Charlson Mary, Wells Martin T, Ullman Ralph, King Fionnuala, Shmukler Celia

机构信息

Center for Integrative Medicine, Weill Cornell Medical College, New York, NY, United States of America.

Department of Statistical Science, Cornell University, Ithaca, NY, United States of America.

出版信息

PLoS One. 2014 Dec 3;9(12):e112479. doi: 10.1371/journal.pone.0112479. eCollection 2014.

Abstract

BACKGROUND

Reducing health care costs requires the ability to identify patients most likely to incur high costs. Our objective was to evaluate the ability of the Charlson comorbidity score to predict the individuals who would incur high costs in the subsequent year and to contrast its predictive ability with other commonly used predictors.

METHODS

We contrasted the prior year Charlson comorbidity index, costs, Diagnostic Cost Group (DCG) and hospitalization as predictors of subsequent year costs from claims data of fund that provides comprehensive health benefits to a large union of health care workers. Total costs in the subsequent year was the principal outcome.

RESULTS

Of the 181,764 predominantly Black and Latino beneficiaries, 70% were adults (mean age 45.7 years; 62% women). As the comorbidity index increased, total yearly costs increased significantly (P<.001). At lower comorbidity, the costs were similar across different chronic diseases. Using regression to predict total costs, top 5th and 10th percentile of costs, the comorbidity index, prior costs and DCG achieved almost identical explained variance in both adults and children.

CONCLUSIONS AND RELEVANCE

The comorbidity index predicted health costs in the subsequent year, performing as well as prior cost and DCG in identifying those in the top 5% or 10%. The comorbidity index can be used prospectively to identify patients who are likely to incur high costs.

TRIAL REGISTRATION

ClinicalTrials.gov NCT01761253.

摘要

背景

降低医疗成本需要具备识别最有可能产生高额费用患者的能力。我们的目标是评估查尔森合并症评分预测次年可能产生高额费用个体的能力,并将其预测能力与其他常用预测指标进行对比。

方法

我们对比了上一年的查尔森合并症指数、费用、诊断成本组(DCG)和住院情况,以此作为从为一个大型医护人员工会提供全面健康福利的基金理赔数据中预测次年费用的指标。次年的总费用是主要结果。

结果

在181,764名主要为黑人和拉丁裔的受益人中,70%为成年人(平均年龄45.7岁;62%为女性)。随着合并症指数的增加,年度总费用显著增加(P<0.001)。在合并症较低时,不同慢性病的费用相似。使用回归分析预测总费用、费用的前5%和10%,合并症指数、既往费用和DCG在成年人和儿童中实现了几乎相同的解释方差。

结论与意义

合并症指数可预测次年的医疗费用,在识别费用处于前5%或10%的人群方面,其表现与既往费用和DCG相当。合并症指数可前瞻性地用于识别可能产生高额费用的患者。

试验注册

ClinicalTrials.gov NCT01761253。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d857/4254512/1766901c6509/pone.0112479.g001.jpg

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