Khedr Eman, Fawi Gharib, Abbas Mohammed Abd Allah, Mohammed Talal A, El-Fetoh Noha Abo, Al Attar Ghada, Noaman Mostafa, Zaki Ahmed F
Departments of Neuropsychiatry, Faculty of Medicine, Assiut University, Assiut, Egypt and head of Departments of Neuropsychiatry, Faculty of Medicine, Aswan University, Aswan, Egypt.
Departments of Neuropsychiatry, Faculty of Medicine, Sohag University, Sohag, Egypt.
J Alzheimers Dis. 2015;45(1):117-26. doi: 10.3233/JAD-142655.
There are only a few reports which provide prevalence rates of mild cognitive impairment (MCI) and dementia specifically in Arabic countries.
This study is aimed at estimating the prevalence of MCI and dementia among subjects aged ≥60 years using door-to-door survey in Qena Governorate/Egypt.
We conducted a door-to-door survey with multistage probability random sampling. Screening of all subjects aged ≥60 years (n = 691) employed a simple questionnaire including changes in memory, behavior, and daily activity, Memory and Executive Screening test (MES)as well as the Mini-Mental State Examination. Suspected cases were referred to the hospital for full clinical examination, DSM-IV diagnostic criteria, Hachinski Ischemic Score, neuroimaging, and laboratory investigations if indicated.
Of the 691 participants, 12 cases had MCI, giving a crude prevalence rate (CPR) of 1.74/100 and 35 were identified as positive for dementia with a CPR of 5.07/100. The highest age-specific prevalence rates were recorded among subjects ≥85 years old (100/100). The CPRs were significantly higher in urban than rural areas (7.1 versus 3.27/100, respectively; p = 0.03), in industrial areas than non-industrial areas (13.23 versus 1.99; p = 0.00001), and in illiterate than literate participants (10.12 versus 2.25/100; p = 0.00001).
Overall, the prevalence rate of MCI and dementia were lower in Qena/Egypt than in other countries. Advanced age, illiteracy, and living in an industrial area were found to be associated with dementia.
仅有少数报告提供了阿拉伯国家轻度认知障碍（MCI）和痴呆症的患病率。
本研究旨在通过对埃及基纳省进行挨家挨户调查，估计60岁及以上人群中MCI和痴呆症的患病率。
我们采用多阶段概率随机抽样进行挨家挨户调查。对所有60岁及以上的受试者（n = 691）进行筛查，使用一份简单问卷，包括记忆、行为和日常活动的变化、记忆与执行筛查测试（MES）以及简易精神状态检查表。疑似病例被转诊至医院进行全面临床检查、DSM-IV诊断标准、哈金斯基缺血评分、神经影像学检查以及必要时的实验室检查。
在691名参与者中，12例患有MCI，粗患病率（CPR）为1.74/100，35例被确诊为痴呆症阳性，CPR为5.07/100。85岁及以上受试者的年龄特异性患病率最高（100/100）。城市地区的CPR显著高于农村地区（分别为7.1和3.27/100；p = 0.03），工业区高于非工业区（13.23和1.99；p = 0.00001），文盲参与者高于识字参与者（10.12和2.25/100；p = 0.00001）。
总体而言，埃及基纳省的MCI和痴呆症患病率低于其他国家。发现高龄、文盲和居住在工业区与痴呆症有关。
