Van Calcar S C, Liebl B H, Fischer M H, Marlett J A
Department of Nutritional Sciences, University of Wisconsin, Madison 53706.
Am J Clin Nutr. 1989 Aug;50(2):381-90. doi: 10.1093/ajcn/50.2.381.
Growth and nitrogen nutriture were evaluated during a yearlong study of 11 profoundly retarded nonambulatory institutionalized youth who were fed by gastrostomy and received anticonvulsants. The effects of dietary fiber and vitamin D were assessed by determining plasma levels and balances of zinc, magnesium, calcium, and phosphorus in a subset of six patients. Increase in body weight was 3.4 +/- 2.4 kg (means + SD), in height, 5.9 +/- 3.9 cm during the year. N balance remained positive throughout the study. Zn and Ca balances suggested that needs for this population may be greater than or equal to 150% of the Recommended Dietary Allowance. Vitamin D supplementation had no effect. Soy polysaccharide fiber intakes of 18-24 g/d compared with 0 or 12-20 g fiber/d significantly improved N and P retentions. Although the determination of nutrient needs of a severely disabled population is complex, our results suggest N and energy but not Zn and Ca allowances for a healthy population may be satisfactory guidelines.
在一项为期一年的研究中,对11名严重智力发育迟缓、非卧床、住在福利院且通过胃造口进食并服用抗惊厥药的青少年的生长和氮营养状况进行了评估。通过测定6名患者亚组的血浆水平以及锌、镁、钙和磷的平衡情况,评估了膳食纤维和维生素D的效果。一年中体重增加了3.4±2.4千克(均值±标准差),身高增加了5.9±3.9厘米。在整个研究过程中氮平衡一直保持为正值。锌和钙的平衡情况表明,该人群的需求量可能大于或等于推荐膳食摄入量的150%。补充维生素D没有效果。大豆多糖纤维摄入量为18 - 24克/天,与摄入量为0或12 - 20克纤维/天相比,显著改善了氮和磷的潴留情况。虽然确定严重残疾人群的营养需求很复杂,但我们的结果表明,健康人群的氮和能量摄入量标准可能是令人满意的指导原则,而锌和钙的摄入量标准并非如此。