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标准与非球面优化轮廓的准分子原位角膜磨镶术临床结果比较：100 只眼 1 年随访的完整病例分析

Comparison of clinical outcomes in PRK with a standard and aspherical optimized profile: a full case analysis of 100 eyes with 1-year follow-up.

作者信息

Dausch Dieter, Dausch Burglinde, Wottke Matthias, Sluyterman van Langeweyde Georg

机构信息

Chung-Ang University, Seoul, South Korea ; Augen-Laser-Klinik Nürnberg, Nuremberg, Germany.

Augen-Laser-Klinik Nürnberg, Nuremberg, Germany.

出版信息

Clin Ophthalmol. 2014 Nov 24;8:2251-60. doi: 10.2147/OPTH.S66608. eCollection 2014.

DOI:10.2147/OPTH.S66608
PMID:25473256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4251749/
Abstract

PURPOSE

One hundred eyes from 55 adult patients with myopia were retrospectively studied to determine the comparative safety, efficacy, and predictability of aberration smart ablation (ASA) and a new advanced ablation algorithm (Triple-A) using the MEL(®) 80 excimer laser.

METHODS

Fifty myopic eyes with a manifest refraction spherical equivalent (MRSE) between -1.0 diopters (D) and -9.75 D were consecutively treated with photorefractive keratec-tomy ASA, and 50 myopic eyes with an MRSE between -1.38 D and -11.0 D with photorefractive keratectomy Triple-A. Uncorrected distance visual acuity, MRSE, the absolute value of the cylinder, corrected distance visual acuity, and postoperative complications at 1 month, 3 months, 6 months, and 12 months (1 year) were descriptively analyzed and compared at 1 year.

RESULTS

After 12 months, the MRSE variance was statistically significantly better in patients triaged to receive Triple-A compared with patients receiving ASA (ASA, ±0.7 D; Triple-A, ±0.15 D; P<0.001). Furthermore, no patient in the Triple-A group had any cylinder postoperatively. Patients in the Triple-A treatment arm achieved a superior result. No statistically significant difference in the two treatment arms was noted for the analysis of the mean MRSE at 12 months (P=0.78).

CONCLUSION

Triple-A was more effective than standard aspherical surgical intervention in a number of treatment outcome parameters (eg, MRSE, astigmatism, efficacy index). The two surgical procedures were equivalent in terms of safety.

摘要

目的

回顾性研究55例成年近视患者的100只眼睛，以确定使用MEL(®) 80准分子激光的像差智能消融术（ASA）和一种新的先进消融算法（Triple-A）的相对安全性、有效性和可预测性。

方法

对50只等效球镜度（MRSE）在-1.0屈光度（D）至-9.75 D之间的近视眼睛连续进行准分子原位角膜磨镶术ASA治疗，对50只MRSE在-1.38 D至-11.0 D之间的近视眼睛进行准分子原位角膜磨镶术Triple-A治疗。对未矫正远视力、MRSE、柱镜绝对值、矫正远视力以及1个月、3个月、6个月和12个月（1年）时的术后并发症进行描述性分析，并在1年时进行比较。

结果

12个月后，接受Triple-A治疗的患者的MRSE方差在统计学上显著优于接受ASA治疗的患者（ASA，±0.7 D；Triple-A，±0.15 D；P<0.001）。此外，Triple-A组没有患者术后出现任何柱镜度数。接受Triple-A治疗组的患者取得了更好的结果。对12个月时的平均MRSE分析显示，两个治疗组之间没有统计学上的显著差异（P=0.78）。

结论

在一些治疗结果参数（如MRSE、散光、疗效指数）方面，Triple-A比标准非球面手术干预更有效。两种手术程序在安全性方面相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/10d86bf88a9d/opth-8-2251Fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/6da791f248c4/opth-8-2251Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/7618bebf16b7/opth-8-2251Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/61cda1258cbe/opth-8-2251Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/f337594d1436/opth-8-2251Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/a6306e58dfe4/opth-8-2251Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/10d86bf88a9d/opth-8-2251Fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/6da791f248c4/opth-8-2251Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/7618bebf16b7/opth-8-2251Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/61cda1258cbe/opth-8-2251Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/f337594d1436/opth-8-2251Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/a6306e58dfe4/opth-8-2251Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ea/4251749/10d86bf88a9d/opth-8-2251Fig6.jpg

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