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应对撒哈拉以南非洲地区日益加重的糖尿病负担:改善中风患者治疗效果的框架

Tackling the growing diabetes burden in Sub-Saharan Africa: a framework for enhancing outcomes in stroke patients.

作者信息

Ovbiagele Bruce

机构信息

Department of Neurology and Neurosurgery, Medical University of South Carolina, 96 Jonathan Lucas Street, CSB 301, MSC 606, Charleston, SC 29425, United States.

出版信息

J Neurol Sci. 2015 Jan 15;348(1-2):136-41. doi: 10.1016/j.jns.2014.11.023. Epub 2014 Nov 26.

DOI:10.1016/j.jns.2014.11.023
PMID:25475149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4298457/
Abstract

According to the World Health Organization (WHO), more than 80% of worldwide diabetes (DM)-related deaths presently occur in low- and middle-income countries (LMIC), and left unchecked these DM-related deaths will likely double over the next 20 years. Cardiovascular disease (CVD) is the most prevalent and detrimental complication of DM: doubling the risk of CVD events (including stroke) and accounting for up to 80% of DM-related deaths. Given the aforementioned, interventions targeted at reducing CVD risk among people with DM are integral to limiting DM-related morbidity and mortality in LMIC, a majority of which are located in Sub-Saharan Africa (SSA). However, SSA is contextually unique: socioeconomic obstacles, cultural barriers, under-diagnosis, uncoordinated care, and shortage of physicians currently limit the capacity of SSA countries to implement CVD prevention among people with DM in a timely and sustainable manner. This article proposes a theory-based framework for conceptualizing integrated protocol-driven risk factor patient self-management interventions that could be adopted or adapted in future studies among hospitalized stroke patients with DM encountered in SSA. These interventions include systematic health education at hospital discharge, use of post-discharge trained community lay navigators, implementation of nurse-led group clinics and administration of health technology (personalized phone text messaging and home tele-monitoring), all aimed at increasing patient self-efficacy and intrinsic motivation for sustained adherence to therapies proven to reduce CVD event risk.

摘要

根据世界卫生组织(WHO)的数据,目前全球超过80%的糖尿病(DM)相关死亡发生在低收入和中等收入国家(LMIC),如果不加以控制,这些与DM相关的死亡在未来20年可能会翻倍。心血管疾病(CVD)是DM最常见且最有害的并发症:使CVD事件(包括中风)的风险翻倍,并占DM相关死亡的80%。鉴于上述情况,针对降低DM患者CVD风险的干预措施对于限制LMIC中与DM相关的发病率和死亡率至关重要,其中大多数国家位于撒哈拉以南非洲(SSA)。然而,SSA情况独特:社会经济障碍、文化壁垒、诊断不足、护理不协调以及医生短缺目前限制了SSA国家及时且可持续地对DM患者实施CVD预防的能力。本文提出了一个基于理论的框架,用于概念化综合协议驱动的风险因素患者自我管理干预措施,这些措施可在未来针对SSA地区住院的DM中风患者的研究中采用或调整。这些干预措施包括出院时的系统健康教育、使用出院后经过培训的社区非专业导航员、实施护士主导的小组诊所以及应用健康技术(个性化手机短信和家庭远程监测),所有这些旨在提高患者自我效能感和内在动力,以持续坚持已证明可降低CVD事件风险的治疗方法。

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