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The tens of thousands of lives saved by randomized clinical trials in critical care.

作者信息

Doig Gordon S, Roberts Ian, Bellomo Rinaldo

机构信息

Northern Clinical School Intensive Care Research Unit, University of Sydney, Sydney, Australia,

出版信息

Intensive Care Med. 2015 Apr;41(4):701-4. doi: 10.1007/s00134-014-3573-4. Epub 2014 Dec 5.

DOI:10.1007/s00134-014-3573-4
PMID:25476983
Abstract
摘要

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Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study.拯救脓毒症运动:一项长达 7.5 年的研究中,绩效指标与结局之间的关系。
Intensive Care Med. 2014 Nov;40(11):1623-33. doi: 10.1007/s00134-014-3496-0. Epub 2014 Oct 1.
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Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.拯救脓毒症运动:严重脓毒症和脓毒性休克管理国际指南,2012 年。
Intensive Care Med. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Epub 2013 Jan 30.
3
An observational study fluid balance and patient outcomes in the Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy trial.
一项观察性研究:随机评估正常与增强替代治疗水平试验中的液体平衡和患者结局。
Crit Care Med. 2012 Jun;40(6):1753-60. doi: 10.1097/CCM.0b013e318246b9c6.
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Mortality after fluid bolus in African children with severe infection.严重感染非洲儿童输液后死亡率。
N Engl J Med. 2011 Jun 30;364(26):2483-95. doi: 10.1056/NEJMoa1101549. Epub 2011 May 26.
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Intensity of continuous renal-replacement therapy in critically ill patients.危重症患者持续肾脏替代治疗的强度
N Engl J Med. 2009 Oct 22;361(17):1627-38. doi: 10.1056/NEJMoa0902413.
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Comparison of two fluid-management strategies in acute lung injury.急性肺损伤中两种液体管理策略的比较
N Engl J Med. 2006 Jun 15;354(24):2564-75. doi: 10.1056/NEJMoa062200. Epub 2006 May 21.
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Crit Care Med. 2006 Jun;34(6):1589-96. doi: 10.1097/01.CCM.0000217961.75225.E9.
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Survival after treatment of rabies with induction of coma.通过诱导昏迷治疗狂犬病后的存活情况。
N Engl J Med. 2005 Jun 16;352(24):2508-14. doi: 10.1056/NEJMoa050382.
9
Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months.MRC CRASH研究的最终结果,一项针对成年颅脑损伤患者静脉注射皮质类固醇的随机安慰剂对照试验——6个月时的结果
Lancet. 2005;365(9475):1957-9. doi: 10.1016/S0140-6736(05)66552-X.
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Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial.静脉注射皮质类固醇对10008例有临床显著意义的头部损伤成人14天内死亡的影响(MRC CRASH试验):随机安慰剂对照试验
Lancet. 2004;364(9442):1321-8. doi: 10.1016/S0140-6736(04)17188-2.