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苍白球梗死继发的主要认知改变和小写症

Major Cognitive Changes and Micrographia following Globus Pallidus Infarct.

作者信息

Nelson Sarah, Toma Hassanain, LaMonica Haley, Chabrashvili Tinatin

机构信息

Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

Royal Columbian Hospital, 330 E Columbia Street, New Westminster, BC, Canada V3L 3W7.

出版信息

Case Rep Neurol Med. 2014;2014:252486. doi: 10.1155/2014/252486. Epub 2014 Nov 12.

DOI:10.1155/2014/252486
PMID:25478259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4247961/
Abstract

Importance. Globus pallidus (GP) lesions are well known to cause motor deficits but are less commonly-and perhaps not conclusively-associated with cognitive problems. Observations. We present a 45-year-old male with no significant neurological or psychological problems who after suffering a GP infarct was subsequently found to have substantial cognitive problems and micrographia. Formal neuropsychological testing was not possible due to lack of patient follow-up. Conclusions and Relevance. Despite the conflicting literature on the association of GP lesions and cognitive deficits, our patient demonstrated significant neuropsychological changes following his stroke. In addition, evidence of micrographia likely adds to the literature on the localization of this finding. Our case thus suggests that neuropsychological testing may be beneficial after GP strokes.

摘要

重要性。众所周知,苍白球(GP)病变会导致运动功能障碍,但与认知问题的关联较少,且可能尚无定论。观察结果。我们报告一名45岁男性,既往无明显神经或心理问题,在发生GP梗死之后,出现了严重的认知问题和书写过小症。由于缺乏对患者的随访,无法进行正式的神经心理学测试。结论及相关性。尽管关于GP病变与认知缺陷之间关联的文献存在矛盾,但我们的患者在中风后出现了明显的神经心理学变化。此外,书写过小症的证据可能会丰富关于这一发现定位的文献。因此,我们的病例表明,GP中风后进行神经心理学测试可能有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddc/4247961/1cbade9c8a66/CRINM2014-252486.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddc/4247961/39a6821c4352/CRINM2014-252486.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddc/4247961/1cbade9c8a66/CRINM2014-252486.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddc/4247961/39a6821c4352/CRINM2014-252486.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddc/4247961/1cbade9c8a66/CRINM2014-252486.002.jpg

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Intern Med. 2012;51(14):1953-4. doi: 10.2169/internalmedicine.51.7721. Epub 2012 Jul 15.
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Neuroanatomy of a neurobehavioral disturbance in the left anterior thalamic infarction.左侧丘脑前梗死所致神经行为障碍的神经解剖学研究。
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Micrographia associated with motor neglect.与运动忽视相关的书写障碍。
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Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia?苍白球 DBS 治疗节段性肌张力障碍引起的手微颤:运动减少的微妙迹象?
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Neurological picture. A case of stroke induced micrographia.神经学表现。一例中风诱发的小写症病例。
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Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: the COMPARE trial.丘脑底核与苍白球内侧部脑深部电刺激治疗帕金森病的认知与情绪:COMPARE试验
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