来自非洲绿猴的猿猴免疫缺陷病毒分离株之间的遗传多样性。
Genetic diversity among simian immunodeficiency virus isolates from African green monkeys.
作者信息
Johnson P R, Gravell M, Allan J, Goldstein S, Olmsted R A, Dapolito G, McGann C, London W T, Purcell R H, Hirsch V M
机构信息
Department of Microbiology, Georgetown University, Washington, DC.
出版信息
J Med Primatol. 1989;18(3-4):271-7.
PMID:2547962
Abstract
To characterize isolates further within the SIVagm subtype, we studied four SIVagm isolates by cross-hybridization, molecular cloning, and nucleotide sequencing. Our results indicate an unexpected degree of genetic variation among isolates within the SIVagm subtype comparable to the variation between SIVmac and HIV-2.
摘要
为了进一步鉴定SIVagm亚型内的分离株，我们通过交叉杂交、分子克隆和核苷酸测序对4株SIVagm分离株进行了研究。我们的结果表明，SIVagm亚型内分离株之间存在意想不到的遗传变异程度，这与SIVmac和HIV-2之间的变异程度相当。
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