Ohmichi M, Tasaka K, Sugita N, Kamata S, Hasegawa T, Tanizawa O
Department of Obstetrics and Gynecology, Osaka University Medical School, Japan.
Obstet Gynecol. 1989 Sep;74(3 Pt 2):469-71.
A case is reported of hydramnios due to excessive fetal urine production associated with congenital mesoblastic nephroma. Rapid growth of a right renal tumor and excessive fetal urine production were detected by measuring the size of the tumor and hourly fetal urine production during the development of hydramnios between 28-34 weeks of gestation. A female infant weighing 2200 g was born at 34 weeks' gestation. She lost 18% of her birth weight in the first 48 hours because of neonatal polyuria. Right nephrectomy and ureterectomy were performed 2 days after birth. After the operation, the neonatal polyuria improved dramatically. The right renal tumor was identified histologically as a mesoblastic nephroma. The importance is stressed of early and correct antenatal diagnosis of a renal tumor and precise estimation of urine production for postnatal management of hemodynamic change in cases of mesoblastic nephroma.
本文报告一例因胎儿尿液生成过多导致羊水过多的病例,该情况与先天性中胚层肾瘤相关。在妊娠28至34周羊水过多发展过程中,通过测量肿瘤大小及每小时胎儿尿量,检测到右肾肿瘤快速生长及胎儿尿液生成过多。一名体重2200克的女婴于妊娠34周出生。由于新生儿多尿,她在出生后的头48小时内体重减轻了18%。出生后2天进行了右肾切除术和输尿管切除术。术后,新生儿多尿情况显著改善。右肾肿瘤经组织学鉴定为中胚层肾瘤。强调了对肾肿瘤进行早期和正确的产前诊断以及精确估计尿量对于中胚层肾瘤病例产后血流动力学变化管理的重要性。