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蓬塞病(结核性风湿症)——病例报告

Poncet's disease (tubercular rheumatism) - a case report.

作者信息

Talukder M K, Islam M I, Rahman S A, Kawser C A

机构信息

Dr Manik Kumar Talukder, Assistant Professor, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

出版信息

Mymensingh Med J. 2014 Oct;23(4):814-7.

PMID:25481609
Abstract

Poncet's disease is a rare condition in childhood. It occurs due to immunological reaction to tubercular protein resulting in reactive arthritis and manifest with polyarthritis associated with features of active tuberculosis. We are reporting a case of Poncet's disease that was initially treated as a case of Juvenile Idiopathic Arthritis (JIA) without any improvement. The diagnosis was made clinically from history and physical findings with supportive radiological findings and confirmed by granulomatous changes on FNAC. Our patient improved dramatically after treatment with anti-tubercular drugs. Though very rare, Poncet's disease should be strongly considered in the differential diagnosis of fever and polyarthritis of obscure cause, especially in tubercular endemic countries like ours.

摘要

蓬塞病在儿童期是一种罕见病症。它是由于对结核蛋白的免疫反应导致反应性关节炎而发生的,表现为多关节炎并伴有活动性结核病的特征。我们报告一例蓬塞病病例,该病例最初被当作幼年特发性关节炎(JIA)进行治疗,但毫无改善。诊断是根据病史和体格检查结果从临床上做出的,有支持性的放射学检查结果,并通过细针穿刺抽吸活检(FNAC)的肉芽肿性改变得以证实。我们的患者在接受抗结核药物治疗后显著好转。尽管极为罕见,但在鉴别诊断原因不明的发热和多关节炎时,尤其是在像我们国家这样结核病流行的国家,应高度考虑蓬塞病。

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