Department of Internal Medicine, Osaka Anti-Tuberculosis Association Osaka Fukujuji Hospital, Japan.
Department of Orthopedic Surgery, Osaka Anti-Tuberculosis Association Osaka Fukujuji Hospital, Japan.
Intern Med. 2022 Nov 1;61(21):3245-3249. doi: 10.2169/internalmedicine.9241-21. Epub 2022 Mar 26.
An 82-year-old man with miliary tuberculosis was admitted to our hospital. Approximately six weeks after starting anti-tuberculosis treatment, he complained of pain in the fingers, wrists, and ankles. A histopathological examination of the synovial biopsy revealed nonspecific chronic inflammation with no granulomas. Culture of the biopsy specimen yielded no acid-fast bacilli. Poncet's disease was diagnosed based on the clinical presentation, with no findings suggestive of other diseases. His joint pain rapidly improved with steroid therapy. Tuberculosis can cause arthritis through immune-mediated mechanisms without direct invasion in an entity known as Poncet's disease.
一位 82 岁的男性患有粟粒性肺结核,被收入我院。开始抗结核治疗大约六周后,他主诉手指、手腕和踝关节疼痛。滑膜活检的组织病理学检查显示非特异性慢性炎症,没有肉芽肿。活检标本的培养没有发现抗酸杆菌。根据临床表现诊断为 Poncet 病,没有其他疾病的迹象。他的关节疼痛在类固醇治疗后迅速改善。结核病可以通过免疫介导机制引起关节炎,而没有直接侵犯,这种情况被称为 Poncet 病。