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FKBP5 allele-specific epigenetic modification in gene by environment interaction.

作者信息

Klengel Torsten, Binder Elisabeth B

机构信息

1] Max Planck Institute of Psychiatry, Department of Translational Research in Psychiatry, Munich, Germany [2] Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Neuropsychopharmacology. 2015 Jan;40(1):244-6. doi: 10.1038/npp.2014.208.

DOI:10.1038/npp.2014.208
PMID:25482174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4262902/
Abstract
摘要

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本文引用的文献

1
Gene-environment interaction.基因-环境交互作用。
Annu Rev Psychol. 2014;65:41-70. doi: 10.1146/annurev-psych-010213-115100.
2
Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions.转录因子占据可以介导调控区域 DNA 甲基化的活跃转变。
PLoS Genet. 2013;9(12):e1003994. doi: 10.1371/journal.pgen.1003994. Epub 2013 Dec 19.
3
Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism.FKBP5 基因座的基因-环境相互作用：敏感时期、机制和多效性。
Genes Brain Behav. 2014 Jan;13(1):25-37. doi: 10.1111/gbb.12104. Epub 2013 Dec 2.
4
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.等位基因特异性 FKBP5 DNA 去甲基化介导基因-儿童期创伤的相互作用。
Nat Neurosci. 2013 Jan;16(1):33-41. doi: 10.1038/nn.3275. Epub 2012 Dec 2.
5
DNA demethylation dynamics.DNA 去甲基化动态。
Cell. 2011 Sep 16;146(6):866-72. doi: 10.1016/j.cell.2011.08.042.
6
Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks.由核受体触发的活性胞嘧啶脱甲基作用涉及DNA链断裂。
Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11112-7. doi: 10.1073/pnas.0601793103. Epub 2006 Jul 13.