Zürch M, Rothhardt J, Hädrich S, Demmler S, Krebs M, Limpert J, Tünnermann A, Guggenmos A, Kleineberg U, Spielmann C
Institute of Optics and Quantum Electronics, Abbe Center of Photonics, Friedrich-Schiller-University Jena, Max-Wien-Platz 1, 07743 Jena, Germany.
1] Institute of Applied Physics, Abbe Center of Photonics, Friedrich-Schiller-University Jena, Albert-Einstein-Straße 15, 07745 Jena, Germany [2] Helmholtz Institute Jena, Fröbelstieg 3, 07743 Jena, Germany.
Sci Rep. 2014 Dec 8;4:7356. doi: 10.1038/srep07356.
Coherent Diffraction Imaging is a technique to study matter with nanometer-scale spatial resolution based on coherent illumination of the sample with hard X-ray, soft X-ray or extreme ultraviolet light delivered from synchrotrons or more recently X-ray Free-Electron Lasers. This robust technique simultaneously allows quantitative amplitude and phase contrast imaging. Laser-driven high harmonic generation XUV-sources allow table-top realizations. However, the low conversion efficiency of lab-based sources imposes either a large scale laser system or long exposure times, preventing many applications. Here we present a lensless imaging experiment combining a high numerical aperture (NA = 0.8) setup with a high average power fibre laser driven high harmonic source. The high flux and narrow-band harmonic line at 33.2 nm enables either sub-wavelength spatial resolution close to the Abbe limit (Δr = 0.8λ) for long exposure time, or sub-70 nm imaging in less than one second. The unprecedented high spatial resolution, compactness of the setup together with the real-time capability paves the way for a plethora of applications in fundamental and life sciences.
相干衍射成像技术是一种基于用来自同步加速器或最近的X射线自由电子激光发出的硬X射线、软X射线或极紫外光对样品进行相干照明,以纳米级空间分辨率研究物质的技术。这种强大的技术同时允许进行定量振幅和相位对比成像。激光驱动的高次谐波产生极紫外光源实现了台式化。然而,基于实验室的光源转换效率低,要么需要大型激光系统,要么需要长时间曝光,这限制了许多应用。在此,我们展示了一个无透镜成像实验,该实验将高数值孔径(NA = 0.8)装置与高平均功率光纤激光驱动的高次谐波源相结合。33.2纳米处的高通量和窄带谐波线,对于长时间曝光,能够实现接近阿贝极限(Δr = 0.8λ)的亚波长空间分辨率,或者在不到一秒的时间内实现亚70纳米成像。前所未有的高空间分辨率、装置的紧凑性以及实时能力为基础科学和生命科学中的大量应用铺平了道路。