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[冻干膜作为分析神经介质受体特性和神经营养剂活性的测试系统]

[Lyophilized membranes as a test system for analyzing the properties of neuromediator receptors and activity of neurotropic agents].

作者信息

Evdokimenko S G, Serebriakova O G, Zaĭtsev S V, Kurochkin I N, Zhukov V P

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1989(5):24-9.

PMID:2548629
Abstract

The effect of lyophilization and prolonged storage of rat brain membrane preparations on the properties of receptors of cholinergic and adrenergic neuromediator systems has been studied by the radioreceptor assay. Lyophilized membrane preparations have been shown to be highly stable as compared with fresh membranes and retain their binding properties during storage for 1 year.

摘要

通过放射受体分析法研究了大鼠脑膜制剂的冻干和长期储存对胆碱能和肾上腺素能神经介质系统受体特性的影响。结果表明,与新鲜膜相比,冻干膜制剂具有高度稳定性,并且在储存1年期间仍保留其结合特性。

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