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[人类和灵长类动物中的免疫缺陷逆转录病毒]

[The immunodeficiency retrovirus in man and primates].

作者信息

Montagnier L

出版信息

Bull Acad Natl Med. 1989 Feb;173(2):185-90; discussion 190-1.

PMID:2548679
Abstract

Human immunodeficiency viruses, HIV-1 and HIV-2, are similar, by genome structure, nucleotide sequences and pathogenicity, to retroviruses existing in various primates, SIVs. The possibility is discussed that the human viruses have their origin in accidental transmission of some monkey viruses to man. Studies of SIVs also suggest that the pathogenic effect not only depends on the virus strain, but also on the host species.

摘要

人类免疫缺陷病毒1型(HIV - 1)和2型(HIV - 2)在基因组结构、核苷酸序列和致病性方面与各种灵长类动物中存在的逆转录病毒——猴免疫缺陷病毒(SIV)相似。人们探讨了人类病毒起源于某些猴病毒意外传播给人类的可能性。对SIV的研究还表明,致病作用不仅取决于病毒毒株,还取决于宿主物种。

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