Busetto Luca, Mozzi Enrico, Schettino Angelo Michele, Furbetta Francesco, Giardiello Cristiano, Micheletto Giancarlo, Pilone Vincenzo
Surg Obes Relat Dis. 2015 Jan-Feb;11(1):110-7. doi: 10.1016/j.soard.2014.04.016. Epub 2014 Apr 28.
Improvements in health-related quality of life (HR-QoL) occur after bariatric surgery. However, sustainability of these changes over time remains debated.
Data collected in a prospective 3-year multicenter Italian study on changes of HR-QoL after laparoscopic adjustable gastric banding were used. HR-QoL has investigated with the SF-36 questionnaire. Hunger, satiety, and the self-perceived effects of LAGB were recorded.
A total of 230 patients (53 male and 177 female) were analyzed. Body mass index was 41.4±5.4 kg/m2 at baseline, declined to 33.8±5.8 kg/m2 12 months after surgery (P<.001), and further reduced to 31.9±5.1 kg/m2 36 months after surgery (P<.001 versus 12 months). Scores in the SF-36 subscales were lower than in the general Italian population at baseline. The physical component summary score was 51.9±11.6 at baseline, improved to 79.2±15.4 at 12 months (P<.001), and stabilized to 79.8±15.6 at 36 months. The mental summary score was 52.3±11.8 at baseline, improved to 75.2±17.3 at 12 months (P<.001), and stabilized to 74.2±17.5 at 36 months. A decline>10 points between 12 and 36 months in the summary scores was observed in 22.0% of the patients for PCS and in 26.8% for MCS. In a multiple linear regression analysis, deterioration in HR-QoL in the 12-36 months period was associated to the presence of better HR-QoL values at 12 months and to a more pronounced reduction of the self-perceived effect of the banding at 36 months.
Improvements in HR-QoL observed in the first year after surgery maintained up to the third year after gastric banding.
减肥手术后健康相关生活质量（HR-QoL）有所改善。然而，这些变化随时间的可持续性仍存在争议。
使用在一项为期3年的意大利前瞻性多中心研究中收集的数据，该研究针对腹腔镜可调节胃束带术后HR-QoL的变化。HR-QoL通过SF-36问卷进行调查。记录饥饿感、饱腹感以及胃束带的自我感知效果。
共分析了230例患者（53例男性和177例女性）。基线时体重指数为41.4±5.4kg/m²，术后12个月降至33.8±5.8kg/m²（P<0.001），术后36个月进一步降至31.9±5.1kg/m²（与12个月时相比P<0.001）。SF-36子量表得分在基线时低于意大利普通人群。身体成分总结得分在基线时为51.9±11.6，12个月时提高到79.2±15.4（P<0.001），36个月时稳定在79.8±15.6。心理总结得分在基线时为52.3±11.8，12个月时提高到75.2±17.3（P<0.001），36个月时稳定在74.2±17.5。在22.0%的患者中观察到身体成分总结得分在12至36个月之间下降>10分，在26.8%的患者中观察到心理成分总结得分下降。在多元线性回归分析中，12至36个月期间HR-QoL的恶化与12个月时更好的HR-QoL值以及36个月时束带自我感知效果更明显的降低有关。
胃束带术后第一年观察到的HR-QoL改善持续到术后第三年。
