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7例癫痫后功能障碍特殊综合征持续超过24小时的临床研究。

Clinical study of seven patients with special syndrome of post-epileptic dysfunction persisting over 24 hours.

作者信息

Yang N, Wang B-G, Zeng W-Y, Zhong Y, Cai X-S, Zheng L-Q, Wu Z-Y, Wang F

机构信息

Department of Neurology, Zhongshan Hospital Affiliated to Guangzhou Medical University of TCM, Zhongshan, Guangdong Province, China.

出版信息

Eur Rev Med Pharmacol Sci. 2014;18(21):3229-33.

PMID:25487933
Abstract

OBJECTIVE

Todd's paralysis is the most common complication after epileptic seizures, especially status epilepticus, but other disabilities deriving from the postictal state are poorly understood. There is relatively little information on the underlying parameters that affect clinical features of post-epileptic dysfunction. The aim of this paper is to investigate clinical features of special post-epileptic dysfunction persisting over 24 hours.

PATIENTS AND METHODS

Seven patients with special syndromes of post-epileptic dysfunction were retrospectively analyzed and the related literature was reviewed.

RESULTS

Six patients with post-epileptic dysfunction experienced status epilepticus. Of the seven patients, six had underlying structural brain lesions. Post-epileptic dysfunction has different syndromes, including post-epileptic paralysis, post-epileptic aphasia, cognitive disorder, gaze palsy and hemianopsia. The duration of the dysfunction in these patients lasted from 2 days to 3 months.

CONCLUSIONS

The great majority of patients with post-epileptic dysfunction experience status epilepticus and have underlying structural brain lesions. Post-epileptic dysfunction includes various syndromes and can last from several days to 3 months with a good prognosis.

摘要

目的

托德麻痹是癫痫发作尤其是癫痫持续状态后最常见的并发症,但对发作后状态导致的其他功能障碍了解甚少。关于影响癫痫发作后功能障碍临床特征的潜在参数的信息相对较少。本文旨在研究持续超过24小时的特殊癫痫发作后功能障碍的临床特征。

患者与方法

回顾性分析7例特殊癫痫发作后功能障碍综合征患者,并复习相关文献。

结果

6例癫痫发作后功能障碍患者发生了癫痫持续状态。7例患者中,6例有潜在的脑结构性病变。癫痫发作后功能障碍有不同的综合征,包括癫痫发作后麻痹、癫痫发作后失语、认知障碍、凝视麻痹和偏盲。这些患者功能障碍的持续时间为2天至3个月。

结论

绝大多数癫痫发作后功能障碍患者发生癫痫持续状态并有潜在的脑结构性病变。癫痫发作后功能障碍包括各种综合征,可持续数天至3个月,预后良好。

相似文献

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Clinical study of seven patients with special syndrome of post-epileptic dysfunction persisting over 24 hours.7例癫痫后功能障碍特殊综合征持续超过24小时的临床研究。
Eur Rev Med Pharmacol Sci. 2014;18(21):3229-33.
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Cognitive dysfunction of right hemisphere-like Todd's paralysis after status epilepticus: a case report.癫痫持续状态后类似托德麻痹的右侧半球认知功能障碍:一例报告
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Recurrent aphasic status epilepticus after prolonged generalized tonic-clonic seizures versus a special feature of Todd's paralysis.持续性失语状态癫痫发作后长时间全身性强直阵挛性发作与 Todd 麻痹的特殊特征。
Epilepsy Behav. 2011 Jan;20(1):132-7. doi: 10.1016/j.yebeh.2010.11.001. Epub 2010 Dec 4.
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Clinical features of Todd's post-epileptic paralysis.托德癫痫后麻痹的临床特征。
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[Variants of Todd's paralysis: postictal apraxia and prolonged postictal hemineglect].[托德麻痹的变体:发作后失用症和发作后长期偏侧忽视]
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